Major depression in the national comorbidity survey-adolescent supplement: prevalence, correlates, and treatment.

Major depression in the national comorbidity survey-adolescent supplement: prevalence, correlates, and treatment.
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DOI:
10.1016/j.jaac.2014.10.010
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发表时间:
2015-01
影响因子:
13.3
通讯作者:
Merikangas, Kathleen Ries
Merikangas, Kathleen Ries
中科院分区:
医学1区
文献类型:
--
作者:
Avenevoli, Shelli;Swendsen, Joel;He, Jian-Ping;Burstein, Marcy;Merikangas, Kathleen Ries

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介绍 DSM-IV 重度抑郁症 (MDD) 和重度 MDD 的 12 个月患病率,检查社会人口统计学相关性和合并症,并描述损害和服务利用情况。数据来自国家合并症调查青少年补充 (NCS-A),这是一项针对 10,123 名 13 至 18 岁青少年的全国代表性调查,使用综合国际诊断访谈 (CIDI) 3.0 版评估 DSM-IV 疾病。每个参与青少年的一名家长或代理人也被要求填写一份自填问卷。 MDD 的终生患病率和 12 个月患病率分别为 11.0% 和 7.5%。相应的重度MDD发生率分别为3.0%和2.3%。 MDD 的患病率在整个青春期显着增加,女性的增幅明显高于男性。大多数 MDD 病例与精神共存疾病和严重的角色障碍有关,并且极少数报告有自杀倾向。重度抑郁症的患病率约为所有抑郁症病例的四分之一;与轻度/中度抑郁症相比,重度抑郁症的损害和临床相关性的估计值高出 2 至 5 倍,自杀念头和行为的发生率明显更高。大多数患有 12 个月 DSM-IV MDD 的青少年 (60.4%) 接受了任何形式的治疗,但只有少数接受了针对疾病的治疗或来自心理健康部门的治疗。研究结果强调了抑郁症对美国青少年的重要公共卫生意义,以及改善这一人群的筛查和治疗机会的迫切需要。
To present the 12-month prevalence of DSM-IV major depressive disorder (MDD) and severe MDD, examine sociodemographic correlates and comorbidity, and describe impairment and service utilization. Data are from the National Comorbidity Survey-Adolescent Supplement (NCS-A), a nationally representative survey of 10,123 adolescents aged 13 to 18 years that assesses DSM-IV disorders using the Composite International Diagnostic Interview (CIDI) Version 3.0. One parent or surrogate of each participating adolescent was also asked to complete a self-administered questionnaire. Lifetime and 12-month prevalence of MDD were 11.0% and 7.5%, respectively. The corresponding rates of severe MDD were 3.0% and 2.3%. The prevalence of MDD increased significantly across adolescence, with markedly greater increases among females than males. Most cases of MDD were associated with psychiatric comorbidity and severe role impairment, and a substantial minority reported suicidality. The prevalence of severe MDD was about a quarter of that of all MDD cases; estimates of impairment and clinical correlates were of 2- to 5-fold greater magnitude for severe versus mild/moderate depression, with markedly higher rates for suicidal thoughts and behaviors. Treatment in any form was received by the majority of adolescents with 12-month DSM-IV MDD (60.4%), but only a minority received treatment that was disorder-specific or from the mental health sector. Findings underscore the important public health significance of depression among US adolescents and the urgent need to improve screening and treatment access in this population.
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