Neonatal Cutaneous Invasive Aspergillosis Accompanied by Hemophagocytic Lymphohistocytosis.
Neonatal Cutaneous Invasive Aspergillosis Accompanied by Hemophagocytic Lymphohistocytosis.
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新生儿皮肤侵袭性曲霉病伴有噬血细胞性淋巴组织细胞增多症。
DOI:
10.1097/inf.0000000000001463
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发表时间:
2017-04
影响因子:
3.6
通讯作者:
Feng Peiying
中科院分区:
文献类型:
--
作者:
Chen Zhuanggui;Yang Lifen;Li Yating;Pan Li;Li Meirong;Al-Hatmi Abdullah M S;Meis Jacques F;Lai Wei;Feng Peiying
We describe a 6-week-old female infant with cutaneous invasive aspergillosis accompanied with hemophagocytic lymphohistocytosis. Aspergillus flavus was isolated from biopsies of necrotic skin lesions on the forehead and scalp; morphologic identification was confirmed by molecular analysis. In vitro antifungal susceptibility testing showed that amphotericin B and triazoles had potent activity. The patient responded well to treatment with intravenous amphotericin B combined with oral posaconazole and local wound care. The hemophagocytic lymphohistocytosis abated after treatment of cutaneous aspergillosis. Both cutaneous invasive aspergillosis and hemophagocytic lymphohistocytosis are severe disorders with high morbidity and mortality requiring prompt diagnosis and treatment.
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影响因子:
3.1
作者:
A. Groll;D. Schrey;A. Tragiannidis;K. Bochennek;T. Lehrnbecher
通讯作者:
A. Groll;D. Schrey;A. Tragiannidis;K. Bochennek;T. Lehrnbecher
DOI:
10.1086/323675
发表时间:
2001-11
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
作者:
L. Sung;S. Weitzman;M. Petrič;S. King;L. Sung
通讯作者:
L. Sung;S. Weitzman;M. Petrič;S. King;L. Sung
影响因子:
10.1
作者:
Lehmberg, Kai;Nichols, Kim E.;Weitzman, Sheila
通讯作者:
Weitzman, Sheila
影响因子:
1.6
作者:
Bernardeschi C;Foulet F;Ingen-Housz-Oro S;Ortonne N;Sitbon K;Quereux G;Lortholary O;Chosidow O;Bretagne S;French Mycosis Study Group
通讯作者:
French Mycosis Study Group
影响因子:
2.4
作者:
M. Isaac
通讯作者:
M. Isaac