The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila
The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila
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与染色质功能相关的两种突变对果蝇雌性生殖细胞的影响
DOI：
10.1007/bf00338393
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
M. Schröder
中科院分区：
文献类型：
--
作者：
J. Szabad;G. Reuter;M. Schröder
我们研究了位置效应杂色突变的两个显性抑制突变对女性生殖系细胞发育的影响。Su-var（2）101和Su-var（3）303在丁酸盐或额外Y染色体的存在下是隐性雌性不育和合子致死。我们分析了具有突变生殖系和正常索马的嵌合体雌性，并得出结论，Su-var（2）1和Su-var（3）3基因的完整功能是索马和生殖系发育所必需的，并且作为间接证据表明，它们的母体提供的产物是正常胚胎发育所必需的。提示果蝇索马、雌性生殖细胞和胚胎细胞的染色质结构和基因表达可能有共同的控制。
SummaryWe have studied the developmental effects of two dominant suppressor mutations of position-effect variegation mutations on female germ-line cells. Su-var (2) 101, which has been shown to affect chromatin structure though altering histone deacetylation, and Su-var (3) 303are recessive female steriles and zygotic lethals in the presence of butyrate or an additional Y chromosome. We have analysed mosaic females with mutant germ-line and normal soma and concluded that intact functions of the Su-var (2) 1 and the Su-var (3) 3 genes are required for development of both the soma and the germ-line and that as indirect evidence suggest, their maternally provided products are needed for normal embryonic development. It is suggested that there is possibly a common control of chromatin structure and gene expression in the soma, female germ-line and embryonic cells of Drosophila.
果蝇 X 染色体 2E-F 区域的发育遗传学：该区域富含“发育重要”基因。
影响因子：
3.3
作者：
Perrimon,N;Engstrom,L;Mahowald,AP
通讯作者：
Mahowald,AP
合子致死突变对果蝇雌性种系功能的影响。
影响因子：
2.7
作者：
Perrimon,N;Engstrom,L;Mahowald,AP
通讯作者：
Mahowald,AP
果蝇 X 染色体 2C-D 区域的发育遗传学。
影响因子：
3.3
作者：
Perrimon,N;Engstrom,L;Mahowald,AP
通讯作者：
Mahowald,AP