Developmental genetics of the 2E-F region of the Drosophila X chromosome: a region rich in "developmentally important" genes.
Developmental genetics of the 2E-F region of the Drosophila X chromosome: a region rich in "developmentally important" genes.
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果蝇 X 染色体 2E-F 区域的发育遗传学:该区域富含“发育重要”基因。
DOI:
10.1093/genetics/108.3.559
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发表时间:
1984
期刊:
影响因子:
3.3
通讯作者:
Mahowald,AP
中科院分区:
文献类型:
--
作者:
Perrimon,N;Engstrom,L;Mahowald,AP
We have analyzed the 2E1-3A1 area of theXchromosome with special attention to loci related to embryogenesis. Published maps indicate that this chromosomal segment contains ten bands. Our genetic analysis has identified 11 complementation groups: one recessive visible (prune), two female steriles and eight lethals. One of the female sterile loci isfs(1)k10for which homozygous females produce both egg chambers and embryos with a dorsalized morphology. The second female sterile is the paternally rescuablefs(1)pecanex in which unrescued embryos have a hypertrophic nervous system. Of the eight lethal complementation groups two are recessive embryonic lethals: hemizygous giant (gt) embryos possess segmental defects, and hemizygous crooked neck (crn) embryos exhibit a twisted phenotype. Analysis of these mutations in the female germ line indicates thatgtdoes not show a maternal effect, whereas normal activity ofcrnis required for germ cell viability. Analysis of the maternal effect in germ line clones of the remaining six recessive lethal complementation groups indicates that four are required for germ cell viability and one produces ambiguous results for survival of the germ cells. The remaining,l(1)pole hole, is a recessive early pupal lethal in which embryos derived from germ line clones and lacking wild-type gene activity exhibit the "torso" or "pole hole" phenotype.
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DOI:
10.1139/g76-092
发表时间:
1976
期刊:
Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie
影响因子:
--
作者:
P. Romans;R. Hodgetts;D. Nash
通讯作者:
D. Nash
DOI:
10.1007/978-1-4684-7968-3_7
发表时间:
1980
期刊:
Basic life sciences
影响因子:
--
作者:
E. Wieschaus
通讯作者:
E. Wieschaus
影响因子:
2.7
作者:
PERRIMON, N;GANS, M
通讯作者:
GANS, M
影响因子:
2.7
作者:
Perrimon,N;Engstrom,L;Mahowald,AP
通讯作者:
Mahowald,AP
影响因子:
3.3
作者:
J. Mohler
通讯作者:
J. Mohler