Longitudinal Examination of Prenatal Tobacco Switching Behaviors and Birth Outcomes, Including Electronic Nicotine Delivery System (ENDS) and Dual Use.
Longitudinal Examination of Prenatal Tobacco Switching Behaviors and Birth Outcomes, Including Electronic Nicotine Delivery System (ENDS) and Dual Use.
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DOI：
10.1007/s10995-021-03161-z
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发表时间：
2021-08
影响因子：
2.3
通讯作者：
Breland A
中科院分区：
文献类型：
--
作者：
Ashford K;McCubbin A;Barnett J;Blair LM;Lei F;Bush H;Breland A
在美国，大约8%的孕妇吸烟，5 - 11.9%的孕妇目前使用ENDS产品。使用ENDS对健康的影响是有争议的;然而，大多数含有尼古丁，已知会导致不良的围产期结果。研究表明，成年ENDS使用者随着时间的推移会显著改变使用行为（转为仅使用传统避孕套或双重使用），从而使检查ENDS使用对健康影响的工作变得复杂。本研究的目的是描述仅使用传统香烟、仅使用ENDS或两者兼而有之的妇女的婴儿的转换行为和相关的出生结局。这是一项对经生物学证实的围产期烟草使用者进行的多中心纵向研究，每三个月评估尼古丁产品的使用情况。出于分析的目的，参与者被定义为转换者，无转换者或戒烟者。出生结果从电子病历中提取。分析包括描述性统计，线性和多变量logistic回归调整年龄，早产，吸烟行为在前三个月，吸烟转换行为和吸烟行为之间的相互作用在前三个月。使用SAS v9.4进行分析，显著性确定为p<0.05。在入组时，48.6%的参与者仅使用传统香烟，41.7%为双重使用者，10%仅使用ENDS。虽然近三分之二的参与者在整个怀孕期间使用相同的烟草产品，但26%的人报告了复杂且不易聚集的转换行为。转换者和非转换者之间的出生结果没有差异;但是，非转换者和戒烟者之间的出生体重出现差异。鉴于ENDS使用对健康影响的数据有限，以及围产期尼古丁使用的已知有害后果，捕获和分类产品转换行为对于告知公众健康至关重要，并且仍然是需要进一步研究的挑战。
In the US, approximately 8% of pregnant women smoke, and 5 to 11.9% currently use ENDS products. The health effects of ENDS use are debated; however, most contain nicotine which is known to cause adverse perinatal outcomes. Studies have shown adult ENDS users significantly alter use behaviors over time (switch to conventional cigarettes-only or dual use) thus complicating efforts to examine health effects of ENDS use. The purpose of this study was to describe switching behaviors and associated birth outcomes among infants of women using conventional cigarettes only, ENDS-only, or both. This was a multisite, longitudinal study of biologically confirmed perinatal tobacco users, with nicotine product use assessed each trimester. For the purpose of analysis, participants were defined as switchers, no-switchers, or quitters. Birth outcomes were abstracted from electronic medical records. Analysis included descriptive statistics, linear and multivariate logistic regression adjusted for age, preterm birth, smoking behavior in the first trimester, and an interaction between smoking switching behavior and smoking behavior in the first trimester. Analysis was conducted using SAS v9.4 with significance determined as p<.05. At enrollment, 48.6% of participants used only conventional cigarettes, 41.7% were dual users, and 10% used ENDS-only. While almost two-thirds of participants used the same tobacco product throughout pregnancy, 26% reported switching behaviors that were complex and not easily clustered. No differences were found in birth outcomes between switchers and no-switchers; however, a difference emerged in birth weight between no-switchers and quitters. Given the limited data on health effects of ENDS use, and the known harmful consequences of perinatal nicotine use, capturing and classifying product switching behaviors is imperative to inform public health, and remains a challenge requiring further research.
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影响因子：
7.2
作者：
Blatt, Kaitlin;Moore, Elizabeth;DeFranco, Emily A.
通讯作者：
DeFranco, Emily A.
影响因子：
3.2
作者：
Bhandari, Naleen Raj;Day, Kanesha D.;Ragland, Denise
通讯作者：
Ragland, Denise
DOI：
10.15585/mmwr.mm6808a1
发表时间：
2019-03-01
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Kapaya, Martha;D'Angelo, Denise V;King, Brian A
通讯作者：
King, Brian A
影响因子：
2.4
作者：
McCubbin, Andrea;Fallin-Bennett, Amanda;Ashford, Kristin
通讯作者：
Ashford, Kristin
影响因子：
6.2
作者：
Whittington, Julie R.;Simmons, Pamela M.;Cardenas, Victor M.
通讯作者：
Cardenas, Victor M.