HIV and syphilis infections and associated factors among patients in treatment at a Specialist Alcohol, Tobacco, and Drugs Center in São Paulo's "Cracolândia".
HIV and syphilis infections and associated factors among patients in treatment at a Specialist Alcohol, Tobacco, and Drugs Center in São Paulo's "Cracolândia".
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DOI：
10.1590/2237-6089-2018-0081
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发表时间：
2020-01
影响因子：
2.6
通讯作者：
Madruga CS
中科院分区：
文献类型：
--
作者：
Ribeiro A;Trevizol A;Oluwoye O;McPherson S;McDonell MG;Briese V;Miguel AC;Fratzinger RC;Laranjeira RR;Alonso AL;Karasin AL;Ribeiro M;Madruga CS
这项研究描述了人类免疫缺陷病毒（HIV）和梅毒在巴西最大的专业药物成瘾中心的流行病学情况。最大的挑战是找到减少不平等和歧视影响的战略，并制定政策保护感染者或有感染风险的个人。在2016年1月1日至5月31日期间，进行了一项横断面研究，所有寻求住院治疗的患者（N = 806）均入组。一个结构化的诊断面试和快速测试进行了初步的，诊断证实了在性病研究实验室（VDRL）进行的测试。HIV感染率为5.86%，梅毒感染率为21.9%。女性患梅毒的可能性几乎是男性的2.5倍。HIV感染与无保护性行为（优势比[OR]：3.27，p = 0.003，95%可信区间[95%CI]：1.51-7.11）和自杀意念（OR：6.63，p = 0.001，95%CI：3.37-14.0）相关。虽然只有1.86%的人报告在其一生中的任何时候注射毒品，但这一变量与艾滋病毒和梅毒都有关。在这种严重的社会脆弱性情景中，艾滋病毒和梅毒感染率上升。在实施具体的预防战略时，应考虑到与艾滋病毒和梅毒有关的风险因素，包括对性传播感染的早期诊断和治疗，以应对性传播感染在这一人群中的迅速蔓延。
This study describes the epidemiological scenario of human immunodeficiency virus (HIV) and syphilis at the biggest specialist drug addiction center in Brazil. The great challenge is to find strategies to reduce the impact of inequality and discrimination and develop policies to protect individuals living with – or at risk of – infections. During the period from January 1 to May 31, 2016, a cross-sectional study was conducted on which all patients (N = 806) seeking inpatient treatment were enrolled. A structured diagnostic interview and rapid tests were conducted initially, and diagnoses were confirmed by tests conducted at a venereal disease research laboratory (VDRL). HIV and syphilis rates were 5.86% and 21.9%, respectively. Women were nearly 2.5 times more likely to have syphilis. HIV infection was associated with unprotected sex (odds ratio [OR]: 3.27, p = 0.003, 95% confidence interval [95%CI]: 1.51–7.11), and suicidal ideation (OR: 6.63, p = 0.001, 95%CI: 3.37–14.0). Although only 1.86% reported injecting drugs at any point during their lifetimes, this variable was associated with both HIV and syphilis. Elevated rates of HIV and syphilis were observed in the context of this severe social vulnerability scenario. The risk factors identified as associated with HIV and syphilis should be taken into consideration for implementation of specific prevention strategies including early diagnosis and treatment of sexually transmitted infections (STI) to tackle the rapid spread of STIs in this population.
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影响因子：
3.8
作者：
Cook, Judith A.;Burke-Miller, Jane K.;Cohen, Mardge H.;Cook, Robert L.;Vlahov, David;Wilson, Tracey E.;Golub, Elizabeth T.;Schwartz, Rebecca M.;Howard, Andrea A.;Ponath, Claudia;Plankey, Michael W.;Levine, Andrea;Grey, Dennis D.
通讯作者：
Grey, Dennis D.
影响因子：
4.4
作者：
Abdalla, Renata Rigacci;Madruga, Clarice S.;Laranjeira, Ronaldo
通讯作者：
Laranjeira, Ronaldo
影响因子：
168.9
作者：
Maartens, Gary;Celum, Connie;Lewin, Sharon R.
通讯作者：
Lewin, Sharon R.
影响因子：
1.5
作者：
Doshi, Rupali Kotwal;Vogenthaler, Nicholas S.;del Rio, Carlos
通讯作者：
del Rio, Carlos
DOI：
10.1111/add.13601
发表时间：
2017-02
期刊：
Addiction (Abingdon, England)
影响因子：
--
作者：
Des Jarlais DC;Arasteh K;McKnight C;Feelemyer J;Campbell AN;Tross S;Cooper HL;Hagan H;Perlman DC
通讯作者：
Perlman DC