Life expectancy at birth for people with serious mental illness and other major disorders from a secondary mental health care case register in London.
Life expectancy at birth for people with serious mental illness and other major disorders from a secondary mental health care case register in London.
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DOI：
10.1371/journal.pone.0019590
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Stewart R
中科院分区：
文献类型：
--
作者：
Chang CK;Hayes RD;Perera G;Broadbent MT;Fernandes AC;Lee WE;Hotopf M;Stewart R
尽管医疗保健有所改善，但严重精神疾病患者(SMI)和普通人群之间的死亡率差距仍然存在，特别是对年轻群体来说。来自伦敦一家大型综合二级精神卫生保健提供商的电子数据库被用来评估SMI诊断对出生时预期寿命的影响。这些人在2009年底之前被诊断患有精神分裂症(精神分裂症、分裂情感障碍、双相情感障碍)、物质使用障碍和抑郁发作/障碍，并在2007-09年间接受南伦敦和伦敦东南部的莫德斯利NHS基金会信托基金(SLAM)的积极审查，样本由SLAM案例登记互动搜索(CRIS)系统检索。我们使用寿命表方法，根据2007-09年间的全国死亡率回报，估计了患有重度精神障碍和每一种诊断的人的出生时预期寿命。共有31,719名年龄在15岁或以上的符合条件的SMI患者进行了分析。其中，1,370人在2007-09年间死亡。与国家数据相比，所有疾病都与预期寿命大幅下降有关：男性损失8.0至14.6岁，女性损失9.8至17.5岁。男性精神分裂症患者(损失14.6岁)和女性分裂情感障碍患者(损失17.5岁)的死亡率最高。严重精神疾病对预期寿命的影响是显著的，通常比吸烟、糖尿病和肥胖症等公认的不良暴露的类似计算影响更高。迫切需要确定和预防过早死亡的原因的战略。
Despite improving healthcare, the gap in mortality between people with serious mental illness (SMI) and general population persists, especially for younger age groups. The electronic database from a large and comprehensive secondary mental healthcare provider in London was utilized to assess the impact of SMI diagnoses on life expectancy at birth. People who were diagnosed with SMI (schizophrenia, schizoaffective disorder, bipolar disorder), substance use disorder, and depressive episode/disorder before the end of 2009 and under active review by the South London and Maudsley NHS Foundation Trust (SLAM) in southeast London during 2007–09 comprised the sample, retrieved by the SLAM Case Register Interactive Search (CRIS) system. We estimated life expectancy at birth for people with SMI and each diagnosis, from national mortality returns between 2007–09, using a life table method. A total of 31,719 eligible people, aged 15 years or older, with SMI were analyzed. Among them, 1,370 died during 2007–09. Compared to national figures, all disorders were associated with substantially lower life expectancy: 8.0 to 14.6 life years lost for men and 9.8 to 17.5 life years lost for women. Highest reductions were found for men with schizophrenia (14.6 years lost) and women with schizoaffective disorders (17.5 years lost). The impact of serious mental illness on life expectancy is marked and generally higher than similarly calculated impacts of well-recognised adverse exposures such as smoking, diabetes and obesity. Strategies to identify and prevent causes of premature death are urgently required.
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影响因子：
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作者：
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通讯作者：
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