Diabetes Mellitus in South Asia

Diabetes Mellitus in South Asia
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南亚的糖尿病

DOI:
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发表时间:
2017
期刊:
影响因子:
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通讯作者:
N. Shiomi
N. Shiomi
中科院分区:
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文献类型:
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作者:
V. Waisundara;N. Shiomi

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南亚地区糖尿病及其并发症的患病率远高于其他发达国家和发展中国家;因此,糖尿病已成为该地区的一个严重问题。虽然南亚糖尿病的患病率很高,但其特征和原因尚未得到很好的阐明。南亚地区85%以上的糖尿病人群患有2型糖尿病,其病因可分为两类:内因/传统原因和快速发展诱发的原因。年龄、性别、饮食和生活方式的改变等因素,包括现代化和城市化导致的身体活动缺乏,是主要的促成因素。与糖尿病相关的大部分医疗费用是由于其后期并发症造成的,并且是无法预防的。因此,糖尿病早期阶段的廉价治疗非常重要。在本综述中,建议采取以下措施作为该疾病发生的预防措施:(1) 通过饮食诱导 UCP1,(2) 增加抗糖尿病生物活性成分和/或食物的摄入量,以及 (3) 通过教育计划和政府政策形成共识。应立即实施糖尿病及其并发症一级和二级预防的国家战略和干预措施,以倡导南亚人群的健康生活。
The prevalence rates of diabetes mellitus and its complications in South Asia are much higher than in other developed and developing countries; therefore, diabetes mellitus has become a serious problem in this region. While the prevalence of diabetes mellitus in South Asia is remarkable, its characteristics and causes have not been well-elucidated. More than 85% of the diabetic population in South Asia suffer from type 2 diabetes, and the causes can be divided into two categories: internal/traditional causes and causes induced by rapid development. Factors such as age, gender, diet and lifestyle changes, including a lack of physical activity caused by modernization and urbanization, are major contributory factors. The majority of the healthcare costs associated with diabetes are due to its later complications and are not preventable. Therefore, inexpensive treatment at an early stage of diabetes is important. In this review, the following are recom - mended as preventive measures of the incidence of the disease: (1) induction of UCP1 through the diet, (2) increasing the intake of antidiabetic bioactive components and/or food and (3) evolution of the consensus through educational programs and government policy. National strategies and interventions should be implemented immediately for both the primary and secondary prevention of diabetes mellitus and its complications in order to advocate healthy living among the South Asian populations.
DOI: 10.1210/jcem.86.11.7992
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