The relationship between self-report and biomarkers of stress in low-income reproductive-age women.

The relationship between self-report and biomarkers of stress in low-income reproductive-age women.
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DOI:
10.1016/j.ajog.2010.08.002
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发表时间:
2010-12
影响因子:
9.8
通讯作者:
Holl JL
Holl JL
中科院分区:
医学1区
文献类型:
--
作者:
Borders AE;Grobman WA;Amsden LB;McDade TW;Sharp LK;Holl JL

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确定低收入育龄妇女自我报告的压力和生物学测量之间是否存在关联。在1999年至2005年期间,从芝加哥1998年福利名册中随机选择育龄妇女,每年进行一次访谈,以评估心理社会,社会经济和健康特征。评估了两种应激敏感生物标志物(EB病毒抗体滴度(EBV)和C反应蛋白(CRP)水平)与自我报告的应激的相关性。在接受采访的206名妇女中,205名(99%)同意提供血液样本。基于年龄、种族、产次、就业、婚姻状况或教育的平均EBV或CRP水平没有差异。报告有较高程度的感知压力或报告有受歧视经历的妇女的EBV水平显著较高(p <0.05)。自我报告的心理社会压力的措施与EBV抗体水平升高在低收入人口的育龄妇女。
To determine if there is an association between self-reported and biologic measures of stress in low-income, reproductive age women. Between 1999 and 2005, randomly selected reproductive age women from the 1998 welfare rolls in Chicago were interviewed yearly to assess psychosocial, socioeconomic, and health characteristics. The association of two stress sensitive biomarkers (Epstein-Barr virus antibody titer (EBV) and C-reactive protein (CRP) level) with self-reported stress was assessed. Of the 206 women interviewed, 205 (99%) agreed to provide a blood sample. There was no difference in mean EBV or CRP levels based on age, race, parity, employment, marital status, or education. Women who reported a higher degree of perceived stress or reported experiences of discrimination had significantly higher levels of EBV (p < .05). Measures of self-reported psychosocial stress are associated with elevated levels EBV antibody in a low-income population of reproductive age women.
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