Pre-transplant cognitive screening is a poor predictor of post-transplant cognitive status.
Pre-transplant cognitive screening is a poor predictor of post-transplant cognitive status.
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DOI:
10.1111/ctr.14798
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发表时间:
2022-11
影响因子:
2.1
通讯作者:
中科院分区:
文献类型:
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Transplant centers hesitate to transplant patients with cognitive impairment. It is unclear if pre-kidney transplant (KT) cognitive screening can predict post-KT cognitive function. We evaluated pre-to post-KT cognitive function with the Montreal Cognitive Assessment (MoCA) in a cohort of 108 patients. We used an adjusted logistic regression model to assess pre- to post-KT changes in cognitive status (continuous variable) and a linear mixed model to assess changes in MoCA scores (categorical variable) pre- to post- KT. The average pre- and post-KT MoCA scores were 25.3±3.0 and 26.4±2.8 respectively. Final pre-KT score did not predict post-KT cognitive status (OR = 1.08; 95% CI: 0.92–1.26; p = 0.35). 32% of the patients with a final pre-KT score ≥26 had at least one post-KT score <26. Conversely, 61% of the patients with a final pre-KT score <26 had at least one post KT score ≥26. In the linear mixed model analysis, the final pre-KT score was associated with a small, clinically insignificant (β = 0.34; 95% CI: 0.19–0.49; p < 0.001) effect on the post-KT score. A low pre-KT MoCA score is not a strong independent predictor of post-KT cognitive function and should not preclude patients from receiving a KT.
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DOI:
10.1053/j.ajkd.2016.11.015
发表时间:
2017-06
期刊:
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子:
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作者:
Drew DA;Weiner DE;Tighiouart H;Duncan S;Gupta A;Scott T;Sarnak MJ
通讯作者:
Sarnak MJ
影响因子:
2.1
作者:
Jurgensen, Andrew;Qannus, Abd Assalam;Gupta, Aditi
通讯作者:
Gupta, Aditi
影响因子:
13.6
作者:
Lepping, Rebecca J.;Montgomery, Robert N.;Gupta, Aditi
通讯作者:
Gupta, Aditi
影响因子:
13.6
作者:
Drew, David A.;Tighiouart, Hocine;Sarnak, Mark J.
通讯作者:
Sarnak, Mark J.
影响因子:
4.2
作者:
通讯作者:
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