COVID-19 vaccine hesitancy among the adult population in Ghana: evidence from a pre-vaccination rollout survey.
COVID-19 vaccine hesitancy among the adult population in Ghana: evidence from a pre-vaccination rollout survey.
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DOI：
10.1186/s41182-021-00357-5
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发表时间：
2021-12-16
影响因子：
4.5
通讯作者：
Gyapong M
中科院分区：
文献类型：
--
作者：
Alhassan RK;Aberese-Ako M;Doegah PT;Immurana M;Dalaba MA;Manyeh AK;Klu D;Acquah E;Ansah EK;Gyapong M
2019 年冠状病毒病 (COVID-19) 已在全球夺去了超过 400 万人的生命，在加纳已有 800 多人死亡。 COVID-19 疫苗是遏制疫情的关键干预措施。全球已接种超过 30 亿剂疫苗，加纳接种超过 80 万剂，疫苗接种覆盖率不到 5%。如果管理不当，恐惧、不确定性、阴谋论和安全担忧仍然是疫苗成功推广的重要威胁。确定公民参与 COVID-19 疫苗试验的可能性的预测因素，并随后在有机会时接受疫苗。该研究是2020年9月18日至10月23日对加纳16个地区的社区成员（n = 1556）进行的一项全国范围在线调查。采用边际效应估计的二元概率回归分析来确定社区成员参与 COVID-19 疫苗试验和接种疫苗意愿的预测因素。大约 60% 的受访者表示他们不会参加 COVID-19 疫苗试验； 65% 的人会接种疫苗，69% 的人会推荐给其他人。 18-48 岁成年人、未婚者和男性自愿参加 COVID-19 疫苗试验、接种疫苗并建议其他人这样做的意愿较高 (p<0.05)。不愿意参加 COVID-19 疫苗试验和接种疫苗的重要预测因素是：已婚人士、女性、穆斯林、老年人、城市化程度较低地区的居民以及受教育程度较低或没有受过正规教育的人 (p<0.05)。不愿参加 COVID-19 疫苗试验和接种疫苗的主要原因包括恐惧、安全担忧、对国家机构缺乏信任、不确定性、政治内涵、精神和宗教信仰。加纳成年人接受 COVID-19 疫苗的可能性很高，但该国不应自满，因为恐惧、安全和不信任是可能加剧疫苗犹豫的重要担忧。 COVID-19 疫苗推广活动应有针对性，并认识到公民对疫苗看法的关键预测因素。考虑到这些教训，将促进加纳为至少 2000 万人接种疫苗以实现群体免疫而做出的努力。在线版本包含可在 10.1186/s41182-021-00357-5 获取的补充材料。
Coronavirus disease 2019 (COVID-19) has already claimed over four million lives globally and over 800 deaths in Ghana. The COVID-19 vaccine is a key intervention towards containing the pandemic. Over three billion doses of the vaccine have already been administered globally and over 800,000 doses administered in Ghana, representing less than 5% vaccination coverage. Fear, uncertainty, conspiracy theories and safety concerns remain important threats to, a successful rollout of the vaccine if not managed well. Ascertain the predictors of citizens’ probability of participating in a COVID-19 vaccine trial and subsequently accept the vaccine when given the opportunity. The study was an online nation-wide survey among community members (n = 1556) from 18th September to 23rd October, 2020 in the 16 regions in Ghana. Binary probit regression analysis with marginal effect estimations was employed to ascertain the predictors of community members’ willingness to participate in a COVID-19 vaccine trial and uptake the vaccine. Approximately 60% of respondents said they will not participate in a COVID-19 vaccine trial; 65% will take the vaccine, while 69% will recommend it to others. Willingness to voluntarily participate in COVID-19 vaccine trial, uptake the vaccine and advise others to do same was higher among adults aged 18–48 years, the unmarried and males (p < 0.05). Significant predictors of unwillingness to participate in the COVID-19 vaccine trial and uptake of the vaccine are: married persons, females, Muslims, older persons, residents of less urbanised regions and persons with lower or no formal education (p < 0.05). Predominant reasons cited for unwillingness to participate in a COVID-19 vaccine trial and take the vaccine included fear, safety concerns, lack of trust in state institutions, uncertainty, political connotations, spiritual and religious beliefs. The probability of accepting COVID-19 vaccine among the adult population in Ghana is high but the country should not get complacent because fear, safety and mistrust are important concerns that have the potential to entrench vaccine hesitancy. COVID-19 vaccine rollout campaigns should be targeted and cognisant of the key predictors of citizens’ perceptions of the vaccine. These lessons when considered will promote Ghana’s efforts towards vaccinating at least 20 million people to attain herd immunity. The online version contains supplementary material available at 10.1186/s41182-021-00357-5.
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影响因子：
7.8
作者：
Wang J;Jing R;Lai X;Zhang H;Lyu Y;Knoll MD;Fang H
通讯作者：
Fang H
影响因子：
5.5
作者：
Kuter BJ;Browne S;Momplaisir FM;Feemster KA;Shen AK;Green-McKenzie J;Faig W;Offit PA
通讯作者：
Offit PA
影响因子：
4.5
作者：
Kanyike AM;Olum R;Kajjimu J;Ojilong D;Akech GM;Nassozi DR;Agira D;Wamala NK;Asiimwe A;Matovu D;Nakimuli AB;Lyavala M;Kulwenza P;Kiwumulo J;Bongomin F
通讯作者：
Bongomin F
影响因子：
4.8
作者：
Williams, Richard
通讯作者：
Williams, Richard
DOI：
10.1159/000514636
发表时间：
2021
期刊：
Medical principles and practice : international journal of the Kuwait University, Health Science Centre
影响因子：
--
作者：
Alqudeimat Y;Alenezi D;AlHajri B;Alfouzan H;Almokhaizeem Z;Altamimi S;Almansouri W;Alzalzalah S;Ziyab AH
通讯作者：
Ziyab AH