Community engagement and the ethics of global, translational research: a response to Sofaer and Eyal.
Community engagement and the ethics of global, translational research: a response to Sofaer and Eyal.
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DOI：
10.1080/15265161.2010.494223
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发表时间：
2010-08
期刊：
影响因子：
--
通讯作者：
Mitchell M
中科院分区：
文献类型：
--
作者：
Lynch J;Mitchell M
Neema Sofaer和Nir Eyal（2010年）在《翻译研究的多样伦理》一书中指出，对翻译研究的伦理关注，特别是在全球或跨国环境中，是基于对T1研究的研究，而这些反对意见不适用于T2研究。他们的结论是，与T1研究不同，T2研究不包括转化研究中常见的道德问题特征：（1）特殊风险，（2）可疑的收益，（3）缺乏知情同意，（4）财务利益冲突，（5）剥削全球穷人，（6）发达国家和发展中国家之间的差距扩大。通过对这六个特征的研究，他们得出了一系列关于资助和研究监督机制的实用结论。尽管这篇文章在解决研究伦理和转化研究文献中的空白方面具有优势，但明显缺乏全球或跨国研究参与者的声音。在这一讨论中，没有考虑我们如何确保来自全球穷人的研究参与者的意见得到听取。即使对于T2健康服务研究的良性案例，这也令人不安。如果一个社区由于缺乏基础设施或对研究人员和临床医生缺乏信任而不愿意或不能使用健康干预或服务，那么这项研究就没有带来任何好处。例如，研究人员希望研究污染对马萨诸塞州劳伦斯市居民及其健康的影响，他们假设，
In “The Diverse Ethics of Translational Research,” Neema Sofaer and Nir Eyal (2010) argue that ethical concerns about translational research, especially in global or transnational settings, have been based on studies of T1 research and that those objections do not apply to T2 research. They conclude that unlike T1 research, T2 research does not include the morally problematic features typically found in translational research:(1) special risks,(2) questionable benefits,(3) lack of informed consent,(4) financial conflicts of interest,(5) exploitation of the global poor, and (6) increased disparities between developed and developing nations. From their examination of these six features, they develop a set of practical conclusions about funding and research oversight mechanisms.Despite the strengths of the article in addressing a gap in the literature on research ethics and translational research, there is a marked absence: the voice of the global, or transnational, research participant. A consideration of how we ensure that research participants from among the global poor are heard is lacking in this discussion. This is troubling even for benign cases of T2 health services research. If a community will not or cannot use the health intervention or service because of a lack of infrastructure or a lack of trust in researchers and clinicians, then the research has provided no benefit. For example, researchers wanting to study the impact of pollution on the residents of Lawrence, MA, and their health assumed the commu-
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影响因子：
3.1
作者：
Marshall, PA;Rotimi, C
通讯作者：
Rotimi, C
影响因子：
3.7
作者：
Brugge, D;Kole, A
通讯作者：
Kole, A
DOI：
10.1525/jer.2008.3.2.5
发表时间：
2008-06-01
影响因子：
1.3
作者：
Silka, Linda;Cleghorn, G. Dean;Tellez, Trinidad
通讯作者：
Tellez, Trinidad
影响因子：
13.4
作者：
Sofaer, Neema;Eyal, Nir
通讯作者：
Eyal, Nir
影响因子：
12.7
作者：
Green, LW;Mercer, SL
通讯作者：
Mercer, SL