Computerized Planning of Cryosurgery Using Bubble Packing: An Experimental Validation on a Phantom Material.
Computerized Planning of Cryosurgery Using Bubble Packing: An Experimental Validation on a Phantom Material.
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使用气泡堆积的冷冻手术计算机计划：对幻影材料的实验验证。
DOI：
10.1016/j.ijheatmasstransfer.2008.04.045
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发表时间：
2008-11
影响因子：
5.2
通讯作者：
Rabin, Yoed
中科院分区：
文献类型：
--
作者：
Rossia, Michael R.;Tanaka, Daigo;Shimada, Kenji;Rabin, Yoed
目前的研究重点是实验验证一种基于所谓气泡填充法的规划方案。这项研究是正在进行的开发冷冻手术计算机化规划工具的一部分，其中气泡包装先前已被开发为在给定区域内找到初始，均匀分布的冷冻探针的手段；然后使用所谓的力场类比将冷冻探针移动到最佳布局。然而，由于气泡包装所带来的高质量的低温探针分布和低计算成本，有人认为仅基于气泡包装的规划方案可能更具有临床意义。为了验证这一论点，在模拟的前列腺横截面上进行了实验验证，使用明胶溶液作为模拟材料，专有的液氮冷冻探头和模拟尿道加热的冷冻加热器。实验结果与数值模拟结果进行了比较。结果表明，在确定冻结锋位置时，平均误差为0.8 mm，这是前列腺冷冻手术成像中可接受的不确定性水平。
The current study focuses on experimentally validating a planning scheme based on the so-called bubble-packing method. This study is a part of an ongoing effort to develop computerized planning tools for cryosurgery, where bubble packing has been previously developed as a means to find an initial, uniform distribution of cryoprobes within a given domain; the so-called force-field analogy was then used to move cryoprobes to their optimum layout. However, due to the high quality of the cryoprobes’ distribution, suggested by bubble packing and its low computational cost, it has been argued that a planning scheme based solely on bubble packing may be more clinically relevant. To test this argument, an experimental validation is performed on a simulated cross-section of the prostate, using gelatin solution as a phantom material, proprietary liquid-nitrogen based cryoprobes, and a cryoheater to simulate urethral warming. Experimental results are compared with numerically simulated temperature histories resulting from planning. Results indicate an average disagreement of 0.8 mm in identifying the freezing front location, which is an acceptable level of uncertainty in the context of prostate cryosurgery imaging.
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DOI：
10.1115/1.2834304
发表时间：
1998-02-01
影响因子：
1.7
作者：
Rabin, Y;Shitzer, A
通讯作者：
Shitzer, A
影响因子：
3.5
作者：
Baissalov, R;Sandison, GA;Rewcastle, JC
通讯作者：
Rewcastle, JC
影响因子：
2.8
作者：
Rabin, Y;Lung, DC;Stahovich, TF
通讯作者：
Stahovich, TF
影响因子：
3.5
作者：
Baissalov, R;Sandison, GA;Muldrew, K
通讯作者：
Muldrew, K
影响因子：
3.5
作者：
Rabin, Y;Stahovich, TF
通讯作者：
Stahovich, TF