Ovarian hormones, sleep and cognition across the adult female lifespan: An integrated perspective.
Ovarian hormones, sleep and cognition across the adult female lifespan: An integrated perspective.
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DOI：
10.1016/j.yfrne.2017.08.002
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发表时间：
2017-10
影响因子：
7.4
通讯作者：
Lacreuse A
中科院分区：
文献类型：
--
作者：
Gervais NJ;Mong JA;Lacreuse A
女性卵巢功能丧失与睡眠障碍和认知能力下降有关，这表明雌激素和/或孕激素在调节这些症状中起关键作用。卵巢激素对睡眠和认知过程的影响已经在很少交叉的不同研究领域进行了研究。然而，睡眠对认知功能有相当大的影响。鉴于睡眠和认知之间的紧密联系，卵巢激素可能通过调节睡眠间接影响认知的选择性方面。为了支持这一假设，越来越多的证据表明，更年期后睡眠障碍的发展会加速老年女性的认知能力下降和痴呆症。本文从动物和人类文献中得出卵巢激素对成年女性寿命中睡眠和认知的影响的综合观点。
Loss of ovarian function in women is associated with sleep disturbances and cognitive decline, which suggest a key role for estrogens and/or progestins in modulating these symptoms. The effects of ovarian hormones on sleep and cognitive processes have been studied in separate research fields that seldom intersect. However, sleep has a considerable impact on cognitive function. Given the tight connections between sleep and cognition, ovarian hormones may influence selective aspects of cognition indirectly, via the modulation of sleep. In support of this hypothesis, a growing body of evidence indicates that the development of sleep disorders following menopause contributes to accelerated cognitive decline and dementia in older women. This paper draws from both the animal and human literature to present an integrated view of the effects of ovarian hormones on sleep and cognition across the adult female lifespan.
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