Depressive symptom trajectories during and after adjuvant treatment for breast cancer.
Depressive symptom trajectories during and after adjuvant treatment for breast cancer.
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DOI：
10.1007/s12160-013-9550-2
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发表时间：
2014-06
影响因子：
3.8
通讯作者：
Jacobsen, Paul B.
中科院分区：
文献类型：
--
作者：
Donovan, Kristine A.;Gonzalez, Brian D.;Small, Brent J.;Andrykowski, Michael A.;Jacobsen, Paul B.
乳腺癌治疗期间和之后的抑郁症状的过程还不清楚。我们试图使用增长混合模型根据抑郁症状的不同轨迹来识别患者亚组，并确定是否可以通过人口统计学和临床特征以及应对策略来区分亚组。患有早期乳腺癌的女性在三次设计用于反映临床有意义事件的情况下以及在治疗后期间的三次情况下完成流行病学中心抑郁量表。在治疗前完成疾病管理问卷。一个三级混合模型提供了最佳的拟合数据。在单变量分析中，亚组成员资格与婚姻状况、抑郁症史和关注症状显著相关（ps <0.05）。在多变量分析中，婚姻状况和关注症状仍然是亚组成员的重要预测因素（ps < .05）。在乳腺癌辅助治疗期间和之后，可以识别出不同的抑郁轨迹。这些轨迹的预测因素对解决临床人群中的抑郁症状和未来的研究具有重要意义。
The course of depressive symptoms during and after breast cancer treatment is not well understood. We sought to identify patient subgroups based on distinct trajectories of depressive symptoms using growth mixture modeling and determine whether subgroups could be distinguished by demographic and clinical characteristics and coping strategies. Women with early stage breast cancer completed the Center for Epidemiologic Studies–Depression Scale on three occasions designed to reflect clinically meaningful events and on three occasions during the post-treatment period. The Illness Management Questionnaire was completed prior to treatment. A three-class mixture model provided the best fit to the data. In univariate analyses, subgroup membership was significantly (ps < .05) associated with marital status, history of depression and focusing on symptoms. In multivariate analysis, marital status and focusing on symptoms remained significant (ps < .05) predictors of subgroup membership. Distinct trajectories of depression can be identified during and after adjuvant therapy for breast cancer. Predictors of these trajectories have implications for addressing depressive symptoms in this clinical population and for future research.
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影响因子：
4.2
作者：
Donovan, Kristine A.;Small, Brent J.;Jacobsen, Paul B.
通讯作者：
Jacobsen, Paul B.
影响因子：
6.2
作者：
Andrykowski, Michael A.;Donovan, Kristine A.;Laronga, Christine;Jacobsen, Paul B.
通讯作者：
Jacobsen, Paul B.
影响因子：
6.2
作者：
Jacobsen, Paul B.;Donovan, Kristine A.;Andrykowski, Michael A.
通讯作者：
Andrykowski, Michael A.
影响因子：
4.2
作者：
Dunn, Laura B.;Cooper, Bruce A.;Miaskowski, Christine
通讯作者：
Miaskowski, Christine
乳腺晚期癌症患者的精神病发病率：两种自我评价问卷测量的患病率。
影响因子：
8.8
作者：
Hopwood, P;Howell, A;Maguire, P
通讯作者：
Maguire, P