Association between household size and COVID-19: A UK Biobank observational study.
Association between household size and COVID-19: A UK Biobank observational study.
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家庭规模与Covid-19之间的关联：英国生物库观察研究。
DOI：
10.1177/01410768211073923
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发表时间：
2022-04
影响因子：
17.3
通讯作者：
Khunti K
中科院分区：
文献类型：
--
作者：
Gillies CL;Rowlands AV;Razieh C;Nafilyan V;Chudasama Y;Islam N;Zaccardi F;Ayoubkhani D;Lawson C;Davies MJ;Yates T;Khunti K
评估家庭规模与非重度或重度新冠肺炎发病风险之间的关系。纵向观察性研究。这项研究利用了与国家SARS-CoV-2实验室测试数据相联系的英国生物库。在英国生物库中拥有可用家庭规模数据的401,910人。家庭规模分为一人居住、两人家庭和三人或以上家庭。严重新冠肺炎定义为入院或死亡时SARS-CoV-2检测呈阳性，记录的根本原因为新冠肺炎；非严重新冠肺炎定义为社区环境中的阳性检测。Logistic回归模型适用于评估相关性，调整了潜在的混杂因素。在401,910人中，3,612人(1%)被确认在2020年3月16日至2021年3月16日期间患有严重新冠肺炎感染，11,264人(2.8%)为非严重感染。总体而言，与生活在两口之家的个体相比，独居(调整后的优势比：1.24[95%可信区间：1.14至1.36])或生活在三口或更多家庭中的个体(调整后的优势比：1.28[1.17至1.39])患严重新冠肺炎的几率显著更高。对于非严重新冠肺炎感染，与生活在两人家庭中的个体相比，住在一人家庭中的个体的风险较低(调整后的优势比：0.88[0.82比0.93]。严重或非严重新冠肺炎感染的几率与家庭规模有关。更多地了解为什么某些家庭面临的风险更大，对于限制感染的传播非常重要。
To assess the association between household size and risk of non-severe or severe COVID-19. A longitudinal observational study. This study utilised UK Biobank linked to national SARS-CoV-2 laboratory test data. 401,910 individuals with available data on household size in UK Biobank. Household size was categorised as single occupancy, two-person households and households of three or more. Severe COVID-19 was defined as a positive SARS-CoV-2 test on hospital admission or death with COVID-19 recorded as the underlying cause; and non-severe COVID-19 as a positive test from a community setting. Logistic regression models were fitted to assess associations, adjusting for potential confounders. Of 401,910 individuals, 3612 (1%) were identified as having suffered from a severe COVID-19 infection and 11,264 (2.8%) from a non-severe infection, between 16 March 2020 and 16 March 2021. Overall, the odds of severe COVID-19 was significantly higher among individuals living alone (adjusted odds ratio: 1.24 [95% confidence interval: 1.14 to 1.36], or living in a household of three or more individuals (adjusted odds ratio: 1.28 [1.17 to 1.39], when compared to individuals living in a household of two. For non-severe COVID-19 infection, individuals living in a single-occupancy household had lower odds compared to those living in a household of two (adjusted odds ratio: 0.88 [0.82 to 0.93]. Odds of severe or non-severe COVID-19 infection were associated with household size. Increasing understanding of why certain households are more at risk is important for limiting spread of the infection.
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影响因子：
4.1
作者：
Dreyer K;Steventon A;Fisher R;Deeny SR
通讯作者：
Deeny SR
影响因子：
5
作者：
Fry A;Littlejohns TJ;Sudlow C;Doherty N;Adamska L;Sprosen T;Collins R;Allen NE
通讯作者：
Allen NE
DOI：
10.1016/j.ijid.2020.10.063
发表时间：
2021-01
期刊：
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
影响因子：
--
作者：
Federgruen A;Naha S
通讯作者：
Naha S
影响因子：
105.7
作者：
Hutcheon, Jennifer A.;Chiolero, Arnaud;Hanley, James A.
通讯作者：
Hanley, James A.
影响因子：
15.1
作者：
Martin, Christopher A.;Jenkins, David R.;Pareek, Manish
通讯作者：
Pareek, Manish