Exertional dyspnea in heart failure: a symptom unrelated to pulmonary function at rest or during exercise. Duke University Clinical Cardiology Studies (DUCCS) Exercise Group.
Exertional dyspnea in heart failure: a symptom unrelated to pulmonary function at rest or during exercise. Duke University Clinical Cardiology Studies (DUCCS) Exercise Group.
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心力衰竭引起的劳力性呼吸困难：与静息或运动时肺功能无关的症状。
DOI：
10.1016/s0002-8703(98)70314-x
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发表时间：
1998
影响因子：
4.8
通讯作者：
Higginbotham,MB
中科院分区：
文献类型：
--
作者：
Russell,SD;McNeer,FR;Higginbotham,MB
背景呼吸困难是心力衰竭患者的常见症状，其发生机制尚不清楚。本研究的目的是确定心力衰竭患者劳力性呼吸困难症状的相关因素。方法对71例纽约心脏协会心功能分级为II-IV级的患者（平均射血分数30.6%;平均年龄68岁）进行静息肺功能试验和最大心肺运动试验。结果运动高峰期呼吸困难的严重程度（患者在1 - 10的严重程度量表上评定为3 - 10）与静息或运动血流动力学、肺功能或代谢变量（包括峰值摄氧量（VO 2）、每分钟通气量（Ve）和呼吸频率）或衍生变量（包括Ve/VO 2、Ve/VCO 2和呼吸困难指数（Ve/最大自主通气量））无关。此外，这些变量在报告呼吸困难限制运动的患者和疲劳限制运动的患者之间没有差异。结论心力衰竭患者的劳力性呼吸困难症状不是由排尿功能或需求异常决定的。(Am Heart J 1998;135：398-405.）
Background Exertional dyspnea is a common symptom in patients with heart failure, and the mechanisms responsible for the symptom are unknown. The purpose of this study was to identify factors responsible for the symptom of exertional dyspnea in patients with heart failure. Methods Resting pulmonary-function tests and maximal cardiopulmonary exercise tests were performed in 71 patients with New York Heart Association functional class II-IV symptoms (mean ejection fraction 30.6%; mean age, 68 years). Results The severity of dyspnea at peak exercise, which patients rated as 3 to 10 on a 1 to 10 severity scale, did not correlate with rest or exercise hemodynamic, spirometric, or metabolic variables, including peak oxygen uptake (VO2), minute ventilation (Ve), and respiratory rate, or with derived variables including Ve/VO2, Ve/VCO2, and the dyspnea index (Ve/maximum voluntary ventilation). Additionally, these variables did not differ between patients who reported limitation of exercise by dyspnea and those who were limited by fatigue. Conclusions The symptom of exertional dyspnea in patients with heart failure is not determined by abnormalities in ventilatory function or demand. (Am Heart J 1998;135:398-405.)
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慢性心力衰竭的肌肉疲劳和呼吸困难：同一枚硬币的两个方面？
影响因子：
39.3
作者：
A. Clark;J. Sparrow;A. Coats
通讯作者：
A. Coats
DOI：
--
发表时间：
1995
期刊：
影响因子：
--
作者：
P. Haouzi;F. Marchal;A. Huszczuk
通讯作者：
A. Huszczuk
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影响因子：
24
作者：
Kraemer,MD;Kubo,SH;Rector,TS;Brunsvold,N;Bank,AJ
通讯作者：
Bank,AJ
影响因子：
5.7
作者：
K. Wasserman
通讯作者：
K. Wasserman
影响因子：
4.8
作者：
AWAN, NA;EVENSON, MK;MASON, DT
通讯作者：
MASON, DT