PMRD: a curated database for genes and mutants involved in plant male reproduction.
PMRD: a curated database for genes and mutants involved in plant male reproduction.
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DOI：
10.1186/1471-2229-12-215
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发表时间：
2012-11-15
影响因子：
5.3
通讯作者：
Zhang D
中科院分区：
文献类型：
--
作者：
Cui X;Wang Q;Yin W;Xu H;Wilson ZA;Wei C;Pan S;Zhang D
雄性生殖是植物生活史中分离二倍体孢子体和单倍体配子体世代的基本生物学事件，其涉及约20，000个基因的表达。雄性生殖的控制对于植物育种和杂交种子生产也具有重要的经济意义。随着正向和反向遗传学以及基因组技术的出现，大量与男性生殖相关的基因被发现。因此，系统地收集和不断更新与植物雄性生殖相关的基因和突变体的所有可用信息对单个研究人员来说是极具挑战性的。本研究的目的是人工整理这些基因和突变体的信息，并提供一个网络访问的资源，以促进有效的研究植物雄性生殖。植物雄性生殖数据库（PMRD）是一个用于浏览和检索与植物雄性生殖相关的基因和突变体知识的综合性资源库。它是基于文献和生物数据库，包括506个雄性不育基因和484个突变体的雄性生殖缺陷，从各种植物物种。基于基因本体（GO）注释和文献，系统地收集和纳入了与另外3697个男性生殖相关基因相关的信息，并在文本策展中使用，从文献中捕获基因表达和表型信息。PMRD提供了一个Web界面，允许用户轻松访问策划的注释和基因组信息，包括全名，符号，位置，序列，表达模式，基因功能，突变表型，雄性不育类别和相应的出版物。PMRD还提供微型工具来搜索和浏览微阵列数据集中的基因表达模式，运行BLAST搜索，转换基因ID和生成基因网络。此外，数据库中还集成了一个Mediawiki引擎和一个论坛，使用户能够分享知识、发表评论和讨论专题。PMRD提供了遗传学研究和快速增长的基因组信息之间的综合联系。因此，该数据库提供了植物雄性生殖的全球视图，从而有助于这一重要领域的进展。
Male reproduction is an essential biological event in the plant life cycle separating the diploid sporophyte and haploid gametophyte generations, which involves expression of approximately 20,000 genes. The control of male reproduction is also of economic importance for plant breeding and hybrid seed production. With the advent of forward and reverse genetics and genomic technologies, a large number of male reproduction-related genes have been identified. Thus it is extremely challenging for individual researchers to systematically collect, and continually update, all the available information on genes and mutants related to plant male reproduction. The aim of this study is to manually curate such gene and mutant information and provide a web-accessible resource to facilitate the effective study of plant male reproduction. Plant Male Reproduction Database (PMRD) is a comprehensive resource for browsing and retrieving knowledge on genes and mutants related to plant male reproduction. It is based upon literature and biological databases and includes 506 male sterile genes and 484 mutants with defects of male reproduction from a variety of plant species. Based on Gene Ontology (GO) annotations and literature, information relating to a further 3697 male reproduction related genes were systematically collected and included, and using in text curation, gene expression and phenotypic information were captured from the literature. PMRD provides a web interface which allows users to easily access the curated annotations and genomic information, including full names, symbols, locations, sequences, expression patterns, functions of genes, mutant phenotypes, male sterile categories, and corresponding publications. PMRD also provides mini tools to search and browse expression patterns of genes in microarray datasets, run BLAST searches, convert gene ID and generate gene networks. In addition, a Mediawiki engine and a forum have been integrated within the database, allowing users to share their knowledge, make comments and discuss topics. PMRD provides an integrated link between genetic studies and the rapidly growing genomic information. As such this database provides a global view of plant male reproduction and thus aids advances in this important area.
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影响因子：
5.3
作者：
Albert VA;Soltis DE;Carlson JE;Farmerie WG;Wall PK;Ilut DC;Solow TM;Mueller LA;Landherr LL;Hu Y;Buzgo M;Kim S;Yoo MJ;Frohlich MW;Perl-Treves R;Schlarbaum SE;Bliss BJ;Zhang X;Tanksley SD;Oppenheimer DG;Soltis PS;Ma H;DePamphilis CW;Leebens-Mack JH
通讯作者：
Leebens-Mack JH
影响因子：
7.4
作者：
Pina, C;Pinto, F;Becker, JD
通讯作者：
Becker, JD
影响因子：
14.9
作者：
Ouyang S;Zhu W;Hamilton J;Lin H;Campbell M;Childs K;Thibaud-Nissen F;Malek RL;Lee Y;Zheng L;Orvis J;Haas B;Wortman J;Buell CR
通讯作者：
Buell CR
影响因子：
6.9
作者：
Cheung, Alice Y.;Wu, Hen-Ming
通讯作者：
Wu, Hen-Ming
影响因子：
14.9
作者：
Barrett T;Troup DB;Wilhite SE;Ledoux P;Evangelista C;Kim IF;Tomashevsky M;Marshall KA;Phillippy KH;Sherman PM;Muertter RN;Holko M;Ayanbule O;Yefanov A;Soboleva A
通讯作者：
Soboleva A