Autism spectrum disorder research: knowledge mapping of progress and focus between 2011 and 2022.

Autism spectrum disorder research: knowledge mapping of progress and focus between 2011 and 2022.
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DOI:
10.3389/fpsyt.2023.1096769
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发表时间:
2023
影响因子:
4.7
通讯作者:
Wang, Lifang
Wang, Lifang
中科院分区:
医学3区
文献类型:
--
作者:
Jiang, Miaomiao;Lu, Tianlan;Yang, Kang;Li, Xianjing;Zhao, Liyang;Zhang, Dai;Li, Jun;Wang, Lifang

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近年来,对自闭症谱系障碍(ASD)进行了大量的研究。本研究使用文献计量学分析来描述过去十年ASD研究的现状,并确定其趋势和研究前沿。2011年至2022年发表的关于ASD的研究来自Web of Science Core Collection (WoSCC)。使用Bibliometrix、CiteSpace和VOSviewer进行文献计量学分析。系统检索共纳入57,108项研究,文章发表在6,000多份期刊上。论文数量增加了181.7%(2011年2623篇,2021年7390篇)。遗传学领域的文章在免疫学、临床研究和心理学研究中被广泛引用。共现分析显示,“病因机制”、“临床特征”和“干预特征”是ASD研究的三个主要集群。近十年来,与ASD相关的遗传变异受到越来越多的关注,免疫生态失调和肠道微生物群是2015年后新的发展前沿。本研究使用文献计量学方法来可视化和定量地描述过去十年的自闭症研究。神经科学、遗传学、脑成像研究和肠道微生物组研究提高了我们对自闭症的理解。此外,微生物-肠道-脑轴可能是未来ASD的一个令人兴奋的研究方向。因此,本文通过对自闭症文献的直观分析,展现该领域的发展历程、研究热点和前沿趋势,为未来自闭症的发展提供理论参考。
In recent years, a large number of studies have focused on autism spectrum disorder (ASD). The present study used bibliometric analysis to describe the state of ASD research over the past decade and identify its trends and research fronts. Studies on ASD published from 2011 to 2022 were obtained from the Web of Science Core Collection (WoSCC). Bibliometrix, CiteSpace, and VOSviewer were used for bibliometric analysis. A total of 57,108 studies were included in the systematic search, and articles were published in more than 6,000 journals. The number of publications increased by 181.7% (2,623 in 2011 and 7,390 in 2021). The articles in the field of genetics are widely cited in immunology, clinical research, and psychological research. Keywords co-occurrence analysis revealed that “causative mechanisms,” “clinical features,” and “intervention features” were the three main clusters of ASD research. Over the past decade, genetic variants associated with ASD have gained increasing attention, and immune dysbiosis and gut microbiota are the new development frontiers after 2015. This study uses a bibliometric approach to visualize and quantitatively describe autism research over the last decade. Neuroscience, genetics, brain imaging studies, and gut microbiome studies improve our understanding of autism. In addition, the microbe-gut-brain axis may be an exciting research direction for ASD in the future. Therefore, through visual analysis of autism literature, this paper shows the development process, research hotspots, and cutting-edge trends in this field to provide theoretical reference for the development of autism in the future.
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