Urban-rural disparities in mild cognitive impairment and its functional subtypes among community-dwelling older residents in central China.
Urban-rural disparities in mild cognitive impairment and its functional subtypes among community-dwelling older residents in central China.
复制标题
中部地区社区老年居民轻度认知障碍及其功能亚型的城乡差异
DOI：
10.1136/gpsych-2021-100564
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发表时间：
2021
影响因子：
11.9
通讯作者：
Zeng Y
中科院分区：
文献类型：
--
作者：
Liu D;Li L;An L;Cheng G;Chen C;Zou M;Zhang B;Gan X;Xu L;Ou Y;Wu Q;Wang R;Zeng Y
轻度认知障碍（MCI）及其亚型的患病率差异很大，尽管大多数发生在地理上确定的发达国家和地区。在中国中部欠发达的农村地区，对MCI及其亚型的了解较少。本研究旨在比较中国湖北省城乡65岁以上居民MCI及其亚型的患病率。年龄在65岁或以上的参与者在2018年至2019年期间招募。在城市卫生社区中心和乡镇医院进行了面对面的结构化访谈以及临床和神经心理评估。在2644名无痴呆的参与者中，735人患有MCI，总MCI的患病率为27.8%，遗忘型MCI（aMCI）为20.9%，非遗忘型MCI（naMCI）为6.9%。城市和农村MCI患病率分别为20.2%和44.1%。调整人口统计学因素后，总MCI、aMCI和naMCI的患病率在农村和城市之间存在显著差异（调整后的比值比（OR）分别为2.10、1.44和3.76）。亚组分析显示，农村社会经济和生活方式的劣势和MCI及其亚型之间的关联。我们的研究结果表明，MCI在中国中部城市居民中的患病率与上海等其他大都会地区一致，但农村地区的患病率是城市地区的两倍。中国的前瞻性研究和痴呆症预防应集中在农村地区。
Substantial variations in the prevalence of mild cognitive impairment (MCI) and its subtypes have been reported, although mostly in geographically defined developed countries and regions. Less is known about MCI and its subtypes in rural areas of less developed central China. The study aimed to compare the prevalence of MCI and its subtypes in residents aged 65 years or older in urban and rural areas of Hubei Province, China. Participants aged 65 years or older were recruited between 2018 and 2019. Inperson structured interviews and clinical and neuropsychological assessments were performed at city health community centres and township hospitals. Among 2644 participants without dementia, 735 had MCI, resulting in a prevalence of 27.8% for total MCI, 20.9% for amnestic MCI (aMCI) and 6.9% for non-amnestic MCI (naMCI). The prevalence of MCI in urban and rural areas was 20.2% and 44.1%, respectively. After adjusting for demographic factors, the prevalence of total MCI, aMCI and naMCI differed significantly between rural and urban areas (adjusted odds ratio (OR) 2.10, 1.44 and 3.76, respectively). Subgroup analysis revealed an association between rural socioeconomic and lifestyle disadvantage and MCI and its subtypes. Our findings suggest that the prevalence of MCI among urban residents in central China is consistent with that in other metropolis areas, such as Shanghai, but the prevalence in rural areas is twice that in urban areas. Prospective studies and dementia prevention in China should focus on rural areas.
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影响因子：
3.5
作者：
Ji Cheng Ye;Chen Tian Jiao
通讯作者：
Chen Tian Jiao
影响因子：
120.7
作者：
Ball, K;Berch, DB;Willis, SL
通讯作者：
Willis, SL
DOI：
10.1016/s0140-6736(17)31363-6
发表时间：
2017-12-16
期刊：
Lancet (London, England)
影响因子：
--
作者：
Livingston, Gill;Sommerlad, Andrew;Mukadam, Naaheed
通讯作者：
Mukadam, Naaheed
影响因子：
6.3
作者：
Chen, Ke-Liang;Xu, Yan;Guo, Qi-Hao
通讯作者：
Guo, Qi-Hao
影响因子：
--
作者：
Petersen, Ronald C.;Roberts, Rosebud O.;Knopman, David S.;Boeve, Bradley F.;Geda, Yonas E.;Ivnik, Robcrt J.;Smith, Glenn E.;Jack, Clifford R., Jr.
通讯作者：
Jack, Clifford R., Jr.