Physiological reactivity to psychological stress in human pregnancy: current knowledge and future directions.

Physiological reactivity to psychological stress in human pregnancy: current knowledge and future directions.
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DOI:
10.1016/j.pneurobio.2012.07.003
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发表时间:
2012-11
影响因子:
6.7
通讯作者:
Christian, Lisa M.
Christian, Lisa M.
中科院分区:
医学2区
文献类型:
--
作者:
Christian, Lisa M.

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心血管和神经内分泌对急性应激的反应是非妊娠人群健康结果的重要预测因素。生理反应的幅度和持续时间越大,患高血压疾病和糖尿病的风险越高,对传染病的易感性越大,细胞介导的免疫力受到抑制,患抑郁症和焦虑症的风险也越高。妊娠期间的应激反应对产妇健康、分娩结局和胎儿发育有独特的影响。然而,与更大的文献相比,我们对妊娠期过度应激反应的预测因素和后果的理解是有限的。本文回顾了这方面的文献,强调知识的差距和未来的发展方向。
Cardiovascular and neuroendocrine reactivity to acute stress are important predictors of health outcomes in non-pregnant populations. Greater magnitude and duration of physiological responses have been associated with increased risk of hypertensive disorders and diabetes, greater susceptibility to infectious illnesses, suppression of cell-mediated immunity as well as risk for depression and anxiety disorders. Stress reactivity during pregnancy has unique implications for maternal health, birth outcomes, and fetal development. However, as compared to the larger literature, our understanding of the predictors and consequences of exaggerated stress reactivity in pregnancy is limited. This paper reviews the current state of this literature with an emphasis on gaps in knowledge and future directions.
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