Urogenital schistosomiasis in Nigeria post receipt of the largest single praziquantel donation in Africa.
Urogenital schistosomiasis in Nigeria post receipt of the largest single praziquantel donation in Africa.
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DOI：
10.1016/j.actatropica.2021.105916
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发表时间：
2021-07
期刊：
影响因子：
2.7
通讯作者：
Anderson TJC
中科院分区：
文献类型：
--
作者：
Enabulele EE;Platt RN;Adeyemi E;Agbosua E;Aisien MSO;Ajakaye OG;Ali MU;Amaechi EC;Atalabi TE;Auta T;Awosolu OB;Dagona AG;Edo-Taiwo O;Ejikeugwu CEP;Igbeneghu C;Njom VS;Orji MN;Oyinloye FOP;Ozemoka HJ;Ugah UI;Anderson TJC
2016年，默克集团向非洲国家捐赠了最大的单笔吡喹酮，推动了尼日利亚的血吸虫病控制工作。我们检查了来自尼日利亚10个州15个地点和一个国内流离失所者营地的2023名学龄儿童的尿液样本。我们记录到10个州的总体血血吸虫患病率为10.4%，范围在6 - 37%之间，而国内流离失所者营地的患病率为2.9%。所记录的最高感染流行率（37%）来自Minjibir（卡诺州）Wasai Dam地区的人群，而5个地点没有尿液样本呈阳性。我们在87.9%的感染样本中观察到重度感染（≥50个卵/10 ml尿），并且在2名参与者的尿液中同时出现血红梭菌和曼氏梭菌卵。我们记录的总体患病率略高于2015年报告的全国平均水平（9.5%）。我们的研究结果表明，尽管尼日利亚正在使用吡喹酮，但泌尿生殖血吸虫病仍然普遍存在，感染强度很大。为监测尼日利亚血吸虫病控制的效果，需要进行大规模流行病学监测。
Schistosomiasis control efforts in Nigeria received a boost in 2016 when Merck Group made the largest single donation of praziquantel to an African country. We examined urine samples from 2,023 school age children from 15 locations in 10 states and an Internally Displaced Person’s (IDP) camp in Nigeria. We recorded an overall Schistosoma haematobium prevalence of 10.4% in the 10 states that ranged between 6 – 37%, while prevalence in the IDP camp was 2.9%. The highest infection prevalence (37%) recorded was from the population in Wasai Dam area in Minjibir (Kano State), while five locations had no positive urine samples. We observed heavy intensity of infection (≥ 50 eggs/10 ml urine) in 87.9% of infected samples and co-occurrence of the eggs of S. haematobium and S. mansoni in urine for two participants. The overall prevalence we recorded is slightly above the national average (9.5%) reported in 2015. Our findings indicate that despite the ongoing administration of praziquantel in Nigeria, urogenital schistosomiasis is still prevalent with heavy intensity of infection. Large-scale epidemiological monitoring is required to monitor the efficacy of schistosomiasis control in Nigeria.
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影响因子：
4
作者：
Meurs, Lynn;Mbow, Moustapha;Polman, Katja
通讯作者：
Polman, Katja
影响因子：
3.3
作者：
Okoli, EI;Odaibo, AB
通讯作者：
Odaibo, AB
影响因子：
3.7
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Koukounari A;Donnelly CA;Sacko M;Keita AD;Landouré A;Dembelé R;Bosqué-Oliva E;Gabrielli AF;Gouvras A;Traoré M;Fenwick A;Webster JP
通讯作者：
Webster JP
DOI：
10.4103/1319-2442.248286
发表时间：
2018-11-01
影响因子：
0.5
作者：
Yauba, Saad Mohammed;Rabasa, Adamu Ibrahim;Olowu, Wasiu Adekunle
通讯作者：
Olowu, Wasiu Adekunle