Autoimmunity and Graves' disease.
Autoimmunity and Graves' disease.
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DOI:
10.1038/clpt.2012.10
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发表时间:
2012-04
影响因子:
6.7
通讯作者:
中科院分区:
文献类型:
--
作者:
Current treatment options for Graves’ hyperthyroidism and the related ophthalmopathy (GO) are not uniformly effective and carry with them potentially serious side effects. As a result, efforts have been focused on the development of novel therapies. Progress has been made, particularly in the production of thyroid-stimulating hormone receptor (TSHR) antagonists, as either monoclonal blocking antibodies or small-molecule ligands. In addition, rituximab (RTX) is the first targeted biological therapy to be studied as treatment for these conditions.
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影响因子:
5.8
作者:
Neumann, Susanne;Eliseeva, Elena;Gershengorn, Marvin C.
通讯作者:
Gershengorn, Marvin C.
影响因子:
3.2
作者:
Hegedüs L;Smith TJ;Douglas RS;Nielsen CH
通讯作者:
Nielsen CH
影响因子:
6.6
作者:
Bahn, Rebecca S.;Burch, Henry B.;Stan, Marius N.
通讯作者:
Stan, Marius N.
影响因子:
6.6
作者:
Sanders, Jane;Evans, Michele;Smith, Bernard Rees
通讯作者:
Smith, Bernard Rees
DOI:
10.1056/nejmra0905750
发表时间:
2010-02-25
期刊:
The New England journal of medicine
影响因子:
--
作者:
Bahn RS
通讯作者:
Bahn RS