The Potential Impact of Widespread Cessation Treatment for Smokers With Depression.

The Potential Impact of Widespread Cessation Treatment for Smokers With Depression.
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广泛停止治疗对抑郁症的吸烟者的潜在影响。

DOI:
10.1016/j.amepre.2021.04.024
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发表时间:
2021-11
影响因子:
5.5
通讯作者:
Meza R
Meza R
中科院分区:
医学2区
文献类型:
--
作者:
Tam J;Warner KE;Zivin K;Taylor GMJ;Meza R

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专家建议将戒烟治疗纳入美国心理健康环境,但尚未估计这样做对人口健康的益处。本研究模拟了最佳治疗方案和最大潜在戒烟方案下广泛戒烟治疗对抑郁症患者的影响。模拟戒烟干预措施,针对 2020 年至 2100 年因抑郁症就诊的美国成年吸烟者。干预措施包括:(1) 任何治疗(行为咨询、药物治疗、组合治疗)和 (2) 药物治疗(包括咨询),并分别增加心理健康服务的利用。这些与所有重度抑郁症患者戒烟的最大潜在戒烟方案进行了比较。分析于 2016 年至 2020 年进行。到 2100 年,抑郁症患者广泛采用任何治疗方法都将避免 32,000 例死亡,并延长 138,000 生命年;任何治疗加上 100% 心理健康服务利用率将分别导致 53,000 和 231,000 人。药物治疗将避免 125,000 人死亡,延长 540,000 生命年。药物治疗与 100% 心理健康服务利用率相结合将避免 203,000 例死亡,并延长 887,000 生命年。在当前精神卫生服务利用水平(避免 835,000 例死亡,延长 373 万生命年)和 100% 使用水平(避免 111 万人死亡,延长 507 万生命年)下,最佳治疗方案下的健康收益只占最大潜在戒烟方案下预计的一小部分。为抑郁症患者提供戒烟治疗并增加心理健康服务的利用率将减少烟草对该人群造成的损失。如果戒烟治疗更有效,这些收益将会大得多。
Experts recommend integrating smoking-cessation treatments within U.S. mental health settings, but the population health benefits of doing so have not been estimated. This study simulates the impact of widespread cessation treatment for patients with depression under best-case treatment and maximum potential cessation scenarios. Cessation interventions were simulated for U.S. adult smokers seeing a health professional for depression from 2020 to 2100. Interventions included: (1) Any Treatment (behavioral counseling, pharmacological, combination) and (2) Pharmacological Treatment (including counseling), combined with increased mental health service utilization respectively. These were compared to a maximum potential cessation scenario where all patients with major depression quit smoking. Analyses were conducted in 2016–2020. Widespread uptake of Any Treatment among patients with depression would avert 32,000 deaths and result in 138,000 life years gained by 2100; Any Treatment combined with 100% mental health service utilization would result in 53,000 and 231,000, respectively. Pharmacological Treatment would avert 125,000 deaths, with 540,000 life years gained. Pharmacological Treatment combined with 100% mental health service utilization would see 203,000 deaths averted and 887,000 life years gained. Health gains under best-case treatment scenarios represent modest fractions of those projected under maximum potential cessation scenarios at current mental health service utilization levels (835,000 deaths averted, 3.73 million life years gained), and at 100% utilization (1.11 million deaths averted, 5.07 million life years gained). Providing smoking-cessation treatment to patients with depression and increasing mental health service utilization would reduce the toll of tobacco on this population. These gains would be considerably larger if cessation treatments were more effective.
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