Malaria elimination in Malaysia and the rising threat of Plasmodium knowlesi.
Malaria elimination in Malaysia and the rising threat of Plasmodium knowlesi.
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DOI：
10.1186/s40101-020-00247-5
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发表时间：
2020-11-23
影响因子：
3.1
通讯作者：
Ahmed K
中科院分区：
文献类型：
--
作者：
Chin AZ;Maluda MCM;Jelip J;Jeffree MSB;Culleton R;Ahmed K
疟疾是一个重大的公共卫生问题，世界上40%以上的人口（超过33亿人）面临这种疾病的风险。马来西亚已承诺到2020年消除土著人类疟疾传播。本描述性研究的目的是了解马来西亚2000年至2018年的疟疾流行病学，并强调人畜共患疟疾对国家消除疟疾战略计划构成的威胁。疟疾在马来西亚是一种必须呈报的传染病。本研究中使用的数据来自马来西亚卫生部疾病控制司，由马来西亚各地的医院和诊所提供。本研究中使用的人口数据摘自马来西亚统计局。使用Microsoft Excel进行数据分析。用于制图的数据可在EPSG:4326 WGS84 CRS（坐标参考系统）获得。Shapefile从igismap获取。利用QGIS对地图进行制图和绘图。2000年至2007年期间，马来西亚每年报告的疟疾和18-46人死亡中，人类疟疾占100%。2008年至2017年期间，本地疟疾病例从6071例减少到85例（减少98.6%），而在同一时期，人畜共患诺氏疟原虫病例从376例增加到3614例（增加861%）。2018年是马来西亚首次没有报告任何由人类疟疾寄生虫引起的本地疟疾病例。但诺氏疟原虫病例呈上升趋势，全年共报告4131例。虽然诺氏疟原虫病例发病率的增加可归因于各种因素，包括诊断能力的提高、人类疟疾病例的减少和对诺氏疟原虫认识的提高，但超过50%的诺氏疟原虫病例与农业和种植园活动有关，其余很大比例与森林相关活动有关。马来西亚已进入疟疾控制的消除阶段。然而，人畜共患疟疾正呈指数增长，并成为一个重大的公共卫生问题。需要加强部门间合作，以制定更综合的努力来控制人畜共患疟疾。地方政治承诺和世界卫生组织提供的技术支助将有助于作出集中一致的努力，确保国家消除疟疾战略计划取得成功。
Malaria is a major public-health problem, with over 40% of the world’s population (more than 3.3 billion people) at risk from the disease. Malaysia has committed to eliminate indigenous human malaria transmission by 2020. The objective of this descriptive study is to understand the epidemiology of malaria in Malaysia from 2000 through 2018 and to highlight the threat posed by zoonotic malaria to the National Malaria Elimination Strategic Plan. Malaria is a notifiable infection in Malaysia. The data used in this study were extracted from the Disease Control Division, Ministry of Health Malaysia, contributed by the hospitals and health clinics throughout Malaysia. The population data used in this study was extracted from the Department of Statistics Malaysia. Data analyses were performed using Microsoft Excel. Data used for mapping are available at EPSG:4326 WGS84 CRS (Coordinate Reference System). Shapefile was obtained from igismap. Mapping and plotting of the map were performed using QGIS. Between 2000 and 2007, human malaria contributed 100% of reported malaria and 18–46 deaths per year in Malaysia. Between 2008 and 2017, indigenous malaria cases decreased from 6071 to 85 (98.6% reduction), while during the same period, zoonotic Plasmodium knowlesi cases increased from 376 to 3614 cases (an 861% increase). The year 2018 marked the first year that Malaysia did not report any indigenous cases of malaria caused by human malaria parasites. However, there was an increasing trend of P. knowlesi cases, with a total of 4131 cases reported in that year. Although the increased incidence of P. knowlesi cases can be attributed to various factors including improved diagnostic capacity, reduction in human malaria cases, and increase in awareness of P. knowlesi, more than 50% of P. knowlesi cases were associated with agriculture and plantation activities, with a large remainder proportion linked to forest-related activities. Malaysia has entered the elimination phase of malaria control. Zoonotic malaria, however, is increasing exponentially and becoming a significant public health problem. Improved inter-sectoral collaboration is required in order to develop a more integrated effort to control zoonotic malaria. Local political commitment and the provision of technical support from the World Health Organization will help to create focused and concerted efforts towards ensuring the success of the National Malaria Elimination Strategic Plan.
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评估三个快速诊断测试，用于检测疟原虫的人类感染。
影响因子：
3
作者：
Foster D;Cox-Singh J;Mohamad DS;Krishna S;Chin PP;Singh B
通讯作者：
Singh B
影响因子：
56.9
作者：
CHIN, W;CONTACOS, PG;KIMBALL, HR
通讯作者：
KIMBALL, HR
影响因子：
3
作者：
Herdiana H;Cotter C;Coutrier FN;Zarlinda I;Zelman BW;Tirta YK;Greenhouse B;Gosling RD;Baker P;Whittaker M;Hsiang MS
通讯作者：
Hsiang MS
影响因子：
--
作者：
Jeremiah, Ss;Janagond, Anand B;Parija, Subhash Chandra
通讯作者：
Parija, Subhash Chandra
影响因子：
3.8
作者：
Moyes CL;Henry AJ;Golding N;Huang Z;Singh B;Baird JK;Newton PN;Huffman M;Duda KA;Drakeley CJ;Elyazar IR;Anstey NM;Chen Q;Zommers Z;Bhatt S;Gething PW;Hay SI
通讯作者：
Hay SI