Small steps, strong shield: directly measured, moderate physical activity in 65 361 adults is associated with significant protective effects from severe COVID-19 outcomes.
Small steps, strong shield: directly measured, moderate physical activity in 65 361 adults is associated with significant protective effects from severe COVID-19 outcomes.
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DOI：
10.1136/bjsports-2021-105159
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发表时间：
2022-05
影响因子：
18.4
通讯作者：
Patricios J
中科院分区：
文献类型：
--
作者：
Steenkamp L;Saggers RT;Bandini R;Stranges S;Choi YH;Thornton JS;Hendrie S;Patel D;Rabinowitz S;Patricios J
确定确诊为COVID-19的患者中直接测量的身体活动与住院、重症监护室（ICU）入院、通气和死亡率之间的关联。从2020年3月19日至2021年6月30日，65361名确诊为COVID-19的成年患者直接测量的身体活动数据按活动水平分组：低（<60分钟/周），中度（60-149分钟/周）和高活动（≥150分钟/周）。体力活动水平与不良结局风险的相关性采用改良泊松回归进行分析。我们考虑了人口统计学和合并症，包括已知影响COVID-19结局的疾病，以及由约翰霍普金斯调整临床组系统测量的患者复杂性。回归方法进一步验证了贝叶斯网络模型建立了一个有向无环图。高体力活动与较低的住院率相关（风险比，RR 0.66，95% CI 0.63 - 0.70），入住ICU（RR 0.59，95% CI 0.52至0.66）、通气（RR 0.55，95% CI 0.47至0.64）和死亡（RR 0.58，95% CI 0.50至0.68）。中度体力活动也与住院率（RR 0.87，95% CI 0.82 - 0.91）、入住ICU（RR 0.80，95% CI 0.71 - 0.89）、通气（RR 0.73，95% CI 0.62 - 0.84）和死亡（RR 0.79，95% CI 0.69 - 0.91）较低相关。当感染COVID-19时，高和中等体力活动水平的成年人的结果明显好于低活动水平的成年人。定期体力活动的明显保护作用延伸到那些伴随慢性疾病的人。
To determine the association between directly measured physical activity and hospitalisation, intensive care unit (ICU) admission, ventilation and mortality rates in patients with a confirmed diagnosis of COVID-19. Directly measured physical activity data from 65 361 adult patients with a COVID-19 diagnosis from 19 March 2020 to 30 June 2021, were grouped by activity level: low (<60 min/week), moderate (60–149 min/week) and high activity (≥150 min/week). The association of physical activity levels and the risk of adverse outcomes was analysed using modified Poisson regression. We accounted for demographics and comorbidities including conditions known to influence COVID-19 outcomes, as well as patient complexity as measured by the Johns Hopkins Adjusted Clinical Group system. The regression approach was further validated with a Bayesian network model built off a directed acyclic graph. High physical activity was associated with lower rates of hospitalisation (risk ratio, RR 0.66, 95% CI 0.63 to 0.70), ICU admission (RR 0.59, 95% CI 0.52 to 0.66), ventilation (RR 0.55, 95% CI 0.47 to 0.64) and death (RR 0.58, 95% CI 0.50 to 0.68) due to COVID-19 than those who engaged in low physical activity. Moderate physical activity also was associated with lower rates of hospitalisation (RR 0.87, 95% CI 0.82 to 0.91), admission to ICU (RR 0.80, 95% CI 0.71 to 0.89), ventilation (RR 0.73, 95% CI 0.62 to 0.84) and death (RR 0.79, 95% CI 0.69 to 0.91). Adults with high and moderate physical activity levels had significantly better outcomes than those with low activity when contracting COVID-19. The apparent protective effects of regular physical activity extended to those with concomitant chronic medical conditions.
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影响因子：
105.7
作者：
Greenland, Sander;Mansournia, Mohammad Ali;Altman, Douglas G.
通讯作者：
Altman, Douglas G.
影响因子：
1.5
作者：
Hoeger, Werner W. K.;Bond, Laura;Merugu, Sunitha
通讯作者：
Merugu, Sunitha
影响因子：
3.9
作者：
Cho DH;Lee SJ;Jae SY;Kim WJ;Ha SJ;Gwon JG;Choi J;Kim DW;Kim JY
通讯作者：
Kim JY
体育锻炼，健康生活方式与199疾病严重程度之间的关系；一项横断面研究。
DOI：
10.1007/s10389-020-01468-9
发表时间：
2023
期刊：
Zeitschrift fur Gesundheitswissenschaften = Journal of public health
影响因子：
--
作者：
Tavakol Z;Ghannadi S;Tabesh MR;Halabchi F;Noormohammadpour P;Akbarpour S;Alizadeh Z;Nezhad MH;Reyhan SK
通讯作者：
Reyhan SK
影响因子：
18.4
作者：
Sallis, Robert;Young, Deborah Rohm;Cohen, Deborah A.
通讯作者：
Cohen, Deborah A.