Physical Activity and the Risk of COVID-19 Infection and Mortality: A Nationwide Population-Based Case-Control Study.
Physical Activity and the Risk of COVID-19 Infection and Mortality: A Nationwide Population-Based Case-Control Study.
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DOI：
10.3390/jcm10071539
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发表时间：
2021-04-06
影响因子：
3.9
通讯作者：
Kim JY
中科院分区：
文献类型：
--
作者：
Cho DH;Lee SJ;Jae SY;Kim WJ;Ha SJ;Gwon JG;Choi J;Kim DW;Kim JY
众所周知，有规律的身体活动（PA）可以降低发生严重社区获得性感染的风险。我们研究了韩国人群中PA与冠状病毒病（COVID-19）感染引起的发病率和死亡率的关系。纳入了2014年至2017年期间接受严重急性呼吸道冠状病毒2检测阳性并接受公共健康筛查的患者（n = 6288）。年龄和性别匹配的对照组（n = 125,772）从韩国国民健康保险服务数据库中随机选择。休闲时间PA采用自我报告问卷进行评估。患者的平均PA水平低于对照组（558.2±516.3对580.2±525.7代谢当量(MET)-min/周，p = 0.001）。中度至重度PA （MVPA）患者与较低的COVID-19发病风险相关(优势比（OR）， 0.90；95%置信区间（CI）， 0.86-0.95)。此外，MET/周的标准偏差（SD）增加（525.3 MET-min/周）与COVID-19发病率降低4%相关（OR, 0.96; 95% CI, 0.93-0.99）。MVPA和MET/周的SD增量与较低的死亡率相关（MVPA: OR, 0.47; 95% CI, 0.26-0.87；每SD增量：OR， 0.65; 95% CI, 0.48-0.88）。较高水平的常规PA与较低的COVID-19感染和死亡风险相关，这突出了在COVID-19大流行期间保持适当水平的PA和保持社交距离的重要性。
Regular physical activity (PA) is known to reduce the risk of serious community-acquired infections. We examined the association of PA with the morbidity and mortality resulting from coronavirus disease (COVID-19) infection in the South Korean population. Patients who tested positive for severe acute respiratory coronavirus 2 and who underwent public health screening between 2014 and 2017 (n = 6288) were included. Age- and sex-matched controls (n = 125,772) were randomly selected from the Korean National Health Insurance Service database. Leisure-time PA was assessed using a self-reported questionnaire. The mean PA levels were lower in the patient than in the control group (558.2 ± 516.3 vs. 580.2 ± 525.7 metabolic equivalent of task (MET)-min/week, p = 0.001). Patients with moderate to vigorous PA (MVPA) were associated with a lower risk of COVID-19 morbidity (odds ratio (OR), 0.90; 95% confidence interval (CI), 0.86–0.95). In addition, a standard deviation (SD) increment in MET/week (525.3 MET-min/week) was associated with a 4% decrease in the risk of COVID-19 morbidity (OR, 0.96; 95% CI, 0.93–0.99). MVPA and an SD increment in MET/week were associated with lower mortality (MVPA: OR, 0.47; 95% CI, 0.26–0.87; per SD increment: OR, 0.65; 95% CI, 0.48–0.88). Higher levels of regular PA were associated with a lower risk of COVID-19 infection and mortality, highlighting the importance of maintaining appropriate levels of PA along with social distancing amid the COVID-19 pandemic.
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影响因子：
2.9
作者：
Seong SC;Kim YY;Park SK;Khang YH;Kim HC;Park JH;Kang HJ;Do CH;Song JS;Lee EJ;Ha S;Shin SA;Jeong SL
通讯作者：
Jeong SL
DOI：
10.1038/nri2566
发表时间：
2009-06
期刊：
Nature reviews. Immunology
影响因子：
--
作者：
Tracey KJ
通讯作者：
Tracey KJ
影响因子：
8.9
作者：
Popkin, Barry M.;Du, Shufa;Shekar, Meera
通讯作者：
Shekar, Meera
影响因子：
--
作者：
Baik, I;Curhan, GC;Fawzi, WW
通讯作者：
Fawzi, WW
影响因子：
39.3
作者：
Piepoli, Massimo F.;Hoes, Arno W.;Verschuren, W. M. Monique
通讯作者：
Verschuren, W. M. Monique