A statistical test of phylogenies estimated from sequence data.

A statistical test of phylogenies estimated from sequence data.
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根据序列数据估计的系统发育的统计检验。

DOI:
10.1093/oxfordjournals.molbev.a040560
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发表时间:
1989
影响因子:
10.7
通讯作者:
Li,WH
Li,WH
中科院分区:
生物学1区
文献类型:
--
作者:
Li,WH

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提出了一种简单的方法来测试的重要性的分支顺序,估计从蛋白质或DNA序列数据,三个类群。分支顺序推断的转换距离法,假设有一个或两个外群,和分支长度估计的最小二乘法。如果估计的节点间距离显著大于零,则推断的分支顺序被认为是显著的。为了检验这一点,一个公式的变化的节点间的距离已经制定。所提出的统计检验已通过计算机模拟进行了检验。同样的测试也适用于没有外群的四个分类群的情况,如果考虑一棵无根树的话。五个类群的情况下,节间距离的方差公式也已制定。条件下,它是更有效地添加第五个分类单元的序列比做25%以上的核苷酸测序在原来的四个。提出了一种将不同数据的分析结合起来以获得单个P值的方法。最后,应用于人类-黑猩猩-大猩猩问题的测试表明,这个问题尚未解决。
A simple approach to testing the significance of the branching order, estimated from protein or DNA sequence data, of three taxa is proposed. The branching order is inferred by the transformed-distance method, under the assumption that one or two outgroups are available, and the branch lengths are estimated by the least-squares method. The inferred branching order is considered significant if the estimated internodal distance is significantly greater than zero. To test this, a formula for the variance of the internodal distance has been developed. The statistical test proposed has been checked by computer simulation. The same test also applies to the case of four taxa with no outgroup, if one considers an unrooted tree. Formulas for the variances of internodal distances have also been developed for the case of five taxa. Conditions are given under which it is more efficient to add the sequence of a fifth taxon than to do 25% more nucleotide sequencing in each of the original four. A method is presented for combining analyses of disparate data to get a single P value. Finally, the test, applied to the human-chimpanzee-gorilla problem, shows that the issue is not yet resolved.
根据序列数据计算进化树。
DOI: 10.1073/pnas.76.9.4516
发表时间: 1979
影响因子: 11.1
作者:
L. Klotz;N. Komar;R. L. Blanken;R. M. Mitchell
通讯作者: R. M. Mitchell
DOI: 10.1111/j.1558-5646.1983.tb05533.x
发表时间: 1983-01-01
期刊: EVOLUTION
影响因子: 3.3
作者:
TEMPLETON, AR
通讯作者: TEMPLETON, AR
系统发育研究中分歧时间的估计。
DOI: 10.1139/g77-024
发表时间: 1977
期刊: Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie
影响因子: --
作者:
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通讯作者: R. Chakraborty
T.Kitahara 等人:Nucl.Instr.Methods。
DOI: --
发表时间: --
期刊:
影响因子: --
作者:
通讯作者: --
高等灵长类动物基因间 DNA 的分子进化:DNA 变化模式、分子钟和重复序列的进化。
DOI: 10.1093/oxfordjournals.molbev.a040479
发表时间: 1988
影响因子: 10.7
作者:
Maeda,N;Wu,CI;Bliska,J;Reneke,J
通讯作者: Reneke,J