An artificial tendon to connect the quadriceps muscle to the tibia.
An artificial tendon to connect the quadriceps muscle to the tibia.
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DOI：
10.1002/jor.21419
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发表时间：
2011-11
影响因子：
2.8
通讯作者：
Juncosa-Melvin, Natalia
中科院分区：
文献类型：
--
作者：
Melvin, Alan;Litsky, Alan;Mayerson, Joel;Stringer, Keith;Melvin, David;Juncosa-Melvin, Natalia
目前临床上还没有永久性的、可靠的人工肌腱。我们的团队开发了OrthoCoupler™器械，作为一种多功能连接器，一端固定在肌肉上，另一端可适应惰性植入物，如假体骨或骨锚。本研究的目的是评价该器械的四种配置，以替代山羊膝关节的伸肌机制。在肌肉内，四组有：（A）针刺无涂层束，（B）针刺有涂层束，（C）有倒刺无涂层束，和（D）有倒刺有涂层束。从24只山羊的右后肢切除股四头肌肌腱、髌骨和髌腱。随机分配4组（每组n=6），将股四头肌连接至胫骨（使用接骨板）。在术后90天，从每条手术腿和对侧未手术对照组中采集标本，用于机械测试和组织学检查。在强度测试中，手术腿的最大力（与未手术对照组相比），A组为1288±123 N（与1387±118 N相比），B组为1323±144 N（与1396±779 N相比），C组为930±125 N（与1337±126 N相比），D组为968±109 N（与1528±146 N相比）（平均值± SEM）。带针器械组中OrthoCoupler™腿的强度等同于未手术对照组（p=0.6），而两个带倒刺器械组的最大力显著低于其对照组（p=0.001）。我们相信这项技术将为骨科肿瘤学、关节翻修术、肌腱转移和肌腱损伤重建的临床挑战带来改进的手术。
No permanent, reliable artificial tendon exists clinically. Our group developed the OrthoCoupler™ device as a versatile connector, fixed at one end to a muscle, and adaptable at the other end to inert implants such as prosthetic bones or to bone anchors. The objective of this study was to evaluate four configurations of the device to replace the extensor mechanism of the knee in goats. Within muscle, the four groups had: (A) needle-drawn uncoated bundles, (B) needle-drawn coated bundles, (C) barbed uncoated bundles, and (D) barbed coated bundles. The quadriceps tendon, patella, and patellar tendon were removed from the right hind limb in 24 goats. The four groups (n=6 for each) were randomly assigned to connect the quadriceps muscle to the tibia (with a bone plate). Specimens were collected from each operated leg and contralateral unoperated controls both for mechanical testing and histology at 90 days post-surgery. In strength testing, maximum forces in the operated leg (vs. unoperated control) were 1288±123 N (vs. 1387±118 N) for group A, 1323±144 N (vs. 1396±779 N) for group B, 930±125 N (vs. 1337±126 N) for group C, and 968±109 N (vs. 1528±146 N) for group D (mean ± SEM). The strengths of the OrthoCoupler™ legs in the needled device groups were equivalent to unoperated controls (p=0.6), while both barbed device groups had maximum forces significantly lower than their controls (p=0.001). We believe this technology will yield improved procedures for clinical challenges in orthopaedic oncology, revision arthroplasty, tendon transfer, and tendon injury reconstruction.
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DOI：
10.3109/17453679909000997
发表时间：
1999-10-01
期刊：
ACTA ORTHOPAEDICA SCANDINAVICA
影响因子：
--
作者：
Ozaki, T;Kunisada, T;Inoue, H
通讯作者：
Inoue, H
影响因子：
2.8
作者：
Melvin, Alan;Litsky, Alan;Mayerson, Joel;Witte, David;Melvin, David;Juncosa-Melvin, Natalia
通讯作者：
Juncosa-Melvin, Natalia
影响因子：
4.2
作者：
Melvin, DB;Klosterman, B;Clarson, SJ
通讯作者：
Clarson, SJ
影响因子：
--
作者：
RAWLINS, R
通讯作者：
RAWLINS, R
DOI：
10.1111/j.1749-6632.1968.tb20278.x
发表时间：
1968-01-01
影响因子：
5.2
作者：
Davila, J C;Lautsch, E V;Palmer, T E
通讯作者：
Palmer, T E