Macronutrient Intake in Relation to Migraine and Non-Migraine Headaches.

Macronutrient Intake in Relation to Migraine and Non-Migraine Headaches.
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DOI:
10.3390/nu10091309
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发表时间:
2018-09-15
期刊:
影响因子:
5.9
通讯作者:
Galan P
Galan P
中科院分区:
医学2区
文献类型:
--
作者:
Andreeva VA;Szabo de Edelenyi F;Druesne-Pecollo N;Touvier M;Hercberg S;Galan P

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我们调查了平均每日大量营养素摄入量与偏头痛和非偏头痛的关系。这项横断面研究包括8042名男性和23728名女性,他们来自正在进行的以人群为基础的NutriNet-Santée队列。头痛状况通过在线自我报告问卷进行评估(2013-2016)。偏头痛的定义使用已建立的标准,膳食中的常量营养素摄入量通过≥3、24小时饮食记录进行估算。碳水化合物(简单的、复杂的和总的)、蛋白质和脂肪(饱和脂肪酸、单不饱和脂肪酸、多不饱和脂肪酸和总的)的平均日摄入量(g/天)是主要的暴露变量。调整后的性别差异分析(ANOVA)模型符合。男性偏头痛发生率为9.2%(平均年龄54.3±13.3岁),女性偏头痛发生率为25.7%(平均年龄49.6±12.8岁)。在调整后的模型中,我们观察到(1)与非头痛和非偏头痛的男性相比,男性偏头痛患者的蛋白质摄入量(P<0.0001)和总脂肪摄入量(P<0.01)略低;(2)女性偏头痛患者的总脂肪(P<0.02)和总碳水化合物摄入量(P<0.05)略高于非头痛和非偏头痛的女性。这一发现初步支持了偏头痛状态对大量营养素摄入量的性别差异不大,在不同的人群环境中以及纵向上值得证实,并可能有助于为未来预防头痛的饮食干预提供信息。
We investigated the association of mean daily macronutrient intake with migraine and non-migraine headaches. This cross-sectional study included 8042 men and 23,728 women from the ongoing population-based NutriNet-Santé e-cohort. Headache status was assessed via an online self-report questionnaire (2013–2016). Migraine was defined using established criteria and dietary macronutrient intake was estimated via ≥3 24 h dietary records. Mean daily intake (g/day) of carbohydrates (simple, complex, and total), protein, and fat (saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, and total) were the main exposure variables. Adjusted gender-specific analysis of variance (ANOVA) models were fit. Presence of migraines was noted in 9.2% of men (mean age = 54.3 ± 13.3 years) and 25.7% of women (mean age = 49.6 ± 12.8 years). In adjusted models, we observed (1) somewhat lower protein (p < 0.02) and higher total fat (p < 0.01) intake among male migraineurs compared with males without headaches and those with non-migraine headaches; (2) somewhat higher total fat (p < 0.0001) and total carbohydrate intake (p < 0.05) among female migraineurs compared with females without headaches and those with non-migraine headaches. The findings, which provide preliminary support for modest gender-specific differences in macronutrient intake by migraine status, merit confirmation in different population-based settings, as well as longitudinally, and could help to inform future dietary interventions in headache prevention.
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发表时间: 2015-04
期刊: Headache
影响因子: 5
作者:
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发表时间: 2015-01-01
影响因子: 2.9
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DOI: 10.1186/1129-2377-15-69
发表时间: 2014-10-23
期刊: The journal of headache and pain
影响因子: --
作者:
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通讯作者: Barnard ND