Differences of Clinical Characteristics and Drug Prescriptions between Men and Women with COPD in China.
Differences of Clinical Characteristics and Drug Prescriptions between Men and Women with COPD in China.
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DOI：
10.3390/toxics11020102
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发表时间：
2023-01-21
期刊：
影响因子：
4.6
通讯作者：
Chen P
中科院分区：
文献类型：
--
作者：
Zeng Y;Spruit MA;Deng Q;Franssen FME;Chen P
背景：慢性阻塞性肺疾病患者的症状存在性别差异。我们的目标是衡量男性和女性COPD患者之间的差异，重点是风险因素、症状、生活质量和药物处方。方法：采用横断面观察性研究方法，收集中国地区慢性阻塞性肺疾病患者的人口学特征、吸烟史、职业暴露、生物量暴露、肺功能、呼吸困难、生活质量、吸入药物处方等资料。最近邻算法用于匹配年龄、体重指数和肺功能的女性和男性患者(比例为2：1)。结果：与1462名男性相比，731名女性总体受教育程度较低，结婚率较低(P<；0.001)。共有576名女性(90.0%)不吸烟。更多的男性接触职业粉尘(539人(36.9%)比84人(11.5%)，p=0.013)，而更多的女性接触生物质烟雾(330人(45.1%)对392人(26.8%)，p=0.004)。除痰和胸闷外，女性在咳嗽、呼吸困难、活动、自信、睡眠和精力等方面的主诉多于男性(p<；0.05)。此外，服用三联疗法的女性比男性多(236例(36.3%)比388例(31.0%)，p=0.020)。结论：男性和女性COPD患者在生活质量和吸入性用药方面存在明显差异。
Background: Sex differences in symptoms exist in patients with COPD. Our aim is to measure the differences between men and women with COPD, focusing on risk factors, symptoms, quality of life and drug prescriptions. Methods: In this cross-sectional observational study, patients with COPD were collected in China; demographic characteristics, smoking history, occupational exposure, biomass exposure, lung function, dyspnea, quality of life, and prescriptions for inhaled medications were collected. The nearest neighbor algorithm was used to match female and male patients (ratio 2:1) on age, body mass index, and lung function. Results: Compared with 1462 men, the 731 women generally had lower educational levels and were married less (both p < 0.001). A total of 576 (90.0%) women did not smoke cigarettes. More men were exposed to occupational dust (539 (36.9%) vs. 84 (11.5%), p = 0.013), while more women were exposed to biomass smoke (330 (45.1%) vs. 392 (26.8%), p = 0.004). Except for phlegm and chest tightness, women had more complaints than men for cough, breathlessness, activities, confidence, sleep and energy (p < 0.05). In addition, more women were prescribed triple therapy than men (236 (36.3%) vs. 388 (31.0%), p = 0.020). Conclusions: There are obvious discrepancies in the quality of life and use of inhaled medications between male and female patients with COPD.
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DOI：
10.2147/copd.s104947
发表时间：
2016
影响因子：
2.8
作者：
Morishita-Katsu M;Nishimura K;Taniguchi H;Kimura T;Kondoh Y;Kataoka K;Ogawa T;Watanabe F;Arizono S;Nishiyama O;Nakayasu K;Imaizumi K;Hasegawa Y
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DOI：
10.2753/csa0009-4625400405
发表时间：
2008-06-01
期刊：
CHINESE SOCIOLOGY AND ANTHROPOLOGY
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影响因子：
4.3
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DOI：
10.1164/rccm.201110-1917oc
发表时间：
2012-06-15
影响因子：
24.7
作者：
Mehta, Amar J.;Miedinger, David;Kuenzli, Nino
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Kuenzli, Nino
影响因子：
9.6
作者：
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