Stress Reactivity, Social Anxiety, and Alcohol Consumption in People With Alcoholism: A Laboratory Study.

Stress Reactivity, Social Anxiety, and Alcohol Consumption in People With Alcoholism: A Laboratory Study.
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DOI:
10.1080/15504263.2013.778775
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发表时间:
2013-04-01
影响因子:
2.2
通讯作者:
Thomas SE
Thomas SE
中科院分区:
医学4区
文献类型:
--
作者:
Bacon AK;Thomas SE

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社交焦虑可以通过增加对压力事件的反应来维持酒精依赖,通过饮酒来科普压力事件的倾向,或两者兼而有之。目前的研究是对现有数据集的二次分析,该数据集检查了酒精依赖和并发高和低社交焦虑的个体对实验室压力源(特里尔社会压力测试; TSST)的客观和主观压力反应之间的差异,以及压力源之后的酒精消费。40名酒精依赖的参与者(20名女性)被随机分配到TSST条件作为母研究的一部分。事后分析的社交焦虑措施产生高(n = 19)和低(n = 21)的社交焦虑组。参与者完成了TSST,然后是小剂量的他们最喜欢的酒精饮料(目标血液酒精浓度0.03g/dl),以准备随后的实验室饮酒。参与者接受了两杯(共710毫升)啤酒的假啤酒口味测试。通过主观和客观(平均动脉压,血清皮质醇)对TSST的反应性和味觉测试期间的酒精消耗量(消耗的总mls,mls/kg体重和消耗所有可用啤酒的可能性)评估高和低社交焦虑组之间的差异。高和低社交焦虑组之间的压力反应的客观或主观措施没有差异。社交焦虑组在品尝测试中的饮酒量也没有差异。高和低社交焦虑参与者之间没有观察到差异,并发酒精依赖的压力反应或酒精消费后的压力。鉴于本研究中的所有参与者都有酒精依赖,阴性结果可能表明,应激反应和饮酒应对与酒精依赖的发展更相关,一旦依赖发展,其他因素可能会维持酒精使用。
Social anxiety may maintain alcohol dependence through increased reactivity to stressful events, a propensity to drink to cope with stressful events, or both. The current study is a secondary analysis of an existing dataset that examined differences between individuals with alcohol dependence and concurrent high and low social anxiety in objective and subjective stress reactivity to a laboratory stressor (Trier Social Stress Test; TSST), as well as consumption of alcohol following the stressor. Forty participants with alcohol dependence (20 women) were randomly assigned to the TSST condition as part of the parent study. Post-hoc analysis of social anxiety measures yielded high (n = 19) and low (n = 21) social anxiety groups. Participants completed the TSST, followed by a small dose of their favorite alcoholic beverage (target blood alcohol concentration 0.03g/dl) to prime subsequent laboratory drinking. Participants received a sham beer taste test of two glasses (710ml total) of beer. Differences between high and low social anxiety groups was assessed via subjective and objective (mean arterial pressure, serum cortisol) reactivity to the TSST and consumption of alcohol during the taste test (total mls consumed, mls/kg of body weight, and likelihood of consuming all the beer available). No differences emerged in either objective or subjective measures of stress reactivity between high and low socially anxious groups. There were also no differences between social anxiety groups in amount of alcohol consumed during the taste test. No differences were observed between high and low socially anxious participants with concurrent alcohol dependence on stress reactivity or alcohol consumption following a stressor. Given that all participants in this study had alcohol dependence, negative results may suggest that heightened stress reactivity and drinking to cope are more relevant to the development of alcohol dependence and that other factors may maintain alcohol use once dependence has developed.
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