Phospho.ELM: a database of phosphorylation sites--update 2011.

Phospho.ELM: a database of phosphorylation sites--update 2011.
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DOI:
10.1093/nar/gkq1104
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发表时间:
2011-01
影响因子:
14.9
通讯作者:
Diella F
Diella F
中科院分区:
生物学2区
文献类型:
--
作者:
Dinkel H;Chica C;Via A;Gould CM;Jensen LJ;Gibson TJ;Diella F

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Phospho.ELM资源(http:phospho.elm.eu.org)是一个关系数据库,旨在存储从科学文献和磷酸蛋白质组学分析中提取的体内和体外磷酸化数据。该资源已经积极开发了7年多,目前包括42 574个丝氨酸,苏氨酸和酪氨酸非冗余磷酸化位点。已经实施了几个新的功能,如结构无序/有序和可访问性信息和保护评分。此外,磷酸化位点的保守性现在可以直接在用于得分计算的多序列比对上可视化。最后,特别强调与外部资源的连接,如互动网络和其他数据库。
The Phospho.ELM resource (http://phospho.elm.eu.org) is a relational database designed to store in vivo and in vitro phosphorylation data extracted from the scientific literature and phosphoproteomic analyses. The resource has been actively developed for more than 7 years and currently comprises 42 574 serine, threonine and tyrosine non-redundant phosphorylation sites. Several new features have been implemented, such as structural disorder/order and accessibility information and a conservation score. Additionally, the conservation of the phosphosites can now be visualized directly on the multiple sequence alignment used for the score calculation. Finally, special emphasis has been put on linking to external resources such as interaction networks and other databases.
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