SMART 6: recent updates and new developments.
SMART 6: recent updates and new developments.
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DOI：
10.1093/nar/gkn808
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发表时间：
2009-01
影响因子：
14.9
通讯作者：
Bork P
中科院分区：
文献类型：
--
作者：
Letunic I;Doerks T;Bork P
Simple modular architecture research tool （SMART）是一个用于蛋白质结构域识别和注释的在线工具（http://smart.embl.de/）。它为蛋白质和基因结构域结构的探索和比较研究提供了一个用户友好的平台。当前版本的SMART包含784个蛋白质结构域的手动策划模型。最近的发展集中在进一步的数据集成和改进用户友好性。基于完全测序的基因组的基础蛋白质数据库得到了极大的扩展，现在包括630个物种，而之前的版本只有191个。作为将生物途径信息整合到SMART的第一步，我们的领域注释扩展了代谢途径的数据和几个途径资源的链接。交互网络视图被完全重新设计，现在可用于超过200万个蛋白质。除了对数据库的标准web访问外，用户现在还可以使用分布式注释系统（DAS）或通过基于web服务的简单对象访问协议（SOAP）查询SMART。
Simple modular architecture research tool (SMART) is an online tool (http://smart.embl.de/) for the identification and annotation of protein domains. It provides a user-friendly platform for the exploration and comparative study of domain architectures in both proteins and genes. The current release of SMART contains manually curated models for 784 protein domains. Recent developments were focused on further data integration and improving user friendliness. The underlying protein database based on completely sequenced genomes was greatly expanded and now includes 630 species, compared to 191 in the previous release. As an initial step towards integrating information on biological pathways into SMART, our domain annotations were extended with data on metabolic pathways and links to several pathways resources. The interaction network view was completely redesigned and is now available for more than 2 million proteins. In addition to the standard web access to the database, users can now query SMART using distributed annotation system (DAS) or through a simple object access protocol (SOAP) based web service.
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影响因子：
14.9
作者：
von Mering C;Jensen LJ;Kuhn M;Chaffron S;Doerks T;Krüger B;Snel B;Bork P
通讯作者：
Bork P
影响因子：
14.9
作者：
UniProt Consortium
通讯作者：
UniProt Consortium
影响因子：
14.9
作者：
Kanehisa M;Araki M;Goto S;Hattori M;Hirakawa M;Itoh M;Katayama T;Kawashima S;Okuda S;Tokimatsu T;Yamanishi Y
通讯作者：
Yamanishi Y
影响因子：
14.9
作者：
Mulder NJ;Apweiler R;Attwood TK;Bairoch A;Bateman A;Binns D;Bork P;Buillard V;Cerutti L;Copley R;Courcelle E;Das U;Daugherty L;Dibley M;Finn R;Fleischmann W;Gough J;Haft D;Hulo N;Hunter S;Kahn D;Kanapin A;Kejariwal A;Labarga A;Langendijk-Genevaux PS;Lonsdale D;Lopez R;Letunic I;Madera M;Maslen J;McAnulla C;McDowall J;Mistry J;Mitchell A;Nikolskaya AN;Orchard S;Orengo C;Petryszak R;Selengut JD;Sigrist CJ;Thomas PD;Valentin F;Wilson D;Wu CH;Yeats C
通讯作者：
Yeats C
影响因子：
14.9
作者：
Flicek P;Aken BL;Beal K;Ballester B;Caccamo M;Chen Y;Clarke L;Coates G;Cunningham F;Cutts T;Down T;Dyer SC;Eyre T;Fitzgerald S;Fernandez-Banet J;Gräf S;Haider S;Hammond M;Holland R;Howe KL;Howe K;Johnson N;Jenkinson A;Kähäri A;Keefe D;Kokocinski F;Kulesha E;Lawson D;Longden I;Megy K;Meidl P;Overduin B;Parker A;Pritchard B;Prlic A;Rice S;Rios D;Schuster M;Sealy I;Slater G;Smedley D;Spudich G;Trevanion S;Vilella AJ;Vogel J;White S;Wood M;Birney E;Cox T;Curwen V;Durbin R;Fernandez-Suarez XM;Herrero J;Hubbard TJ;Kasprzyk A;Proctor G;Smith J;Ureta-Vidal A;Searle S
通讯作者：
Searle S