Shedding light on nanomedicine.

Shedding light on nanomedicine.
复制标题

散发纳米医学的光。

DOI:
10.1002/wnan.1188
复制
发表时间:
2012-11
影响因子:
8.6
通讯作者:
Kohane, Daniel S.
Kohane, Daniel S.
中科院分区:
医学2区
文献类型:
--
作者:
Tong, Rong;Kohane, Daniel S.

文献摘要

参考文献

被引文献

相似文献

光是可以将其能量转换成不同形式的电磁辐射(例如,热、化学能和声波)。这种性质已经在光疗中被利用(例如,光热疗法和光动力疗法)和光学成像(例如,荧光成像)用于治疗和诊断目的。光控疗法可以提供最小或非侵入性时空控制以及深层组织穿透。纳米技术提供了许多优点,包括选择性靶向组织、延长治疗效果、保护活性有效载荷和改善治疗指数。这篇综述探讨了纳米技术可以为基于光的治疗和诊断带来的进展,反之亦然,包括光触发系统,含有光活性分子的纳米颗粒,以及本身具有光活性的纳米颗粒。光为基础的治疗,如光损伤和光毒性的局限性将进行讨论。
Light is electromagnetic radiation that can convert its energy into different forms (e.g., heat, chemical energy, and acoustic waves). This property has been exploited in phototherapy (e.g., photothermal therapy and photodynamic therapy) and optical imaging (e.g., fluorescence imaging) for therapeutic and diagnostic purposes. Light-controlled therapies can provide minimally or non-invasive spatiotemporal control as well as deep tissue penetration. Nanotechnology provides a numerous advantages, including selective targeting of tissues, prolongation of therapeutic effect, protection of active payloads, and improved therapeutic indices. This review explores the advances that nanotechnology can bring to light-based therapies and diagnostics, and vice versa, including photo-triggered systems, nanoparticles containing photoactive molecules, and nanoparticles that are themselves photoactive. Limitations of light-based therapies such as photic injury and phototoxicity will be discussed.
DOI: 10.1021/ja900591t
发表时间: 2009-04-29
影响因子: 15
作者:
Agasti SS;Chompoosor A;You CC;Ghosh P;Kim CK;Rotello VM
通讯作者: Rotello VM
DOI: 10.1054/bjoc.2001.2170
发表时间: 2001-11-30
影响因子: 8.8
作者:
Carcenac, M;Dorvillius, M;Pèlegrin, A
通讯作者: Pèlegrin, A
基于梳状 PEG 衍生物的生物相容性胶束:形成、表征和光响应性
DOI: 10.1002/marc.201100196
发表时间: 2011-07-15
影响因子: 4.6
作者:
Chen, Chao-Jian;Liu, Gong-Yan;Ji, Jian
通讯作者: Ji, Jian
DOI: 10.1007/s101030200027
发表时间: 2002-01-01
影响因子: 2.1
作者:
Brancaleon, L;Moseley, H
通讯作者: Moseley, H
DOI: 10.1002/anie.200900255
发表时间: 2009-01-01
影响因子: 16.6
作者:
Babin, Jerome;Pelletier, Maxime;Zhao, Yue
通讯作者: Zhao, Yue