Characteristics of SARS-CoV-2 and COVID-19.
Characteristics of SARS-CoV-2 and COVID-19.
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SARS-CoV-2 和 COVID-19 的特征
DOI:
10.1038/s41579-020-00459-7
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发表时间:
2021-03
期刊:
影响因子:
--
通讯作者:
Shi ZL
中科院分区:
文献类型:
--
作者:
Hu B;Guo H;Zhou P;Shi ZL
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we describe the basic virology of SARS-CoV-2, including genomic characteristics and receptor use, highlighting its key difference from previously known coronaviruses. We summarize current knowledge of clinical, epidemiological and pathological features of COVID-19, as well as recent progress in animal models and antiviral treatment approaches for SARS-CoV-2 infection. We also discuss the potential wildlife hosts and zoonotic origin of this emerging virus in detail. In this Review, Shi and colleagues summarize the exceptional amount of research that has characterized acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19) since this virus has swept around the globe. They discuss what we know so far about the emergence and virology of SARS-CoV-2 and the pathogenesis and treatment of COVID-19.
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影响因子:
13.2
作者:
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通讯作者:
Yuen, Kwok-Yung
影响因子:
168.9
作者:
Chan, Jasper Fuk-Woo;Yuan, Shuofeng;Yuen, Kwok-Yung
通讯作者:
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影响因子:
168.9
作者:
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影响因子:
56.9
作者:
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通讯作者:
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DOI:
10.26355/eurrev_202004_20875
发表时间:
2020-04-01
影响因子:
3.3
作者:
Diurno, F.;Numis, F. G.;Facchini, G.
通讯作者:
Facchini, G.