Insect Tc-six4 marks a unit with similarity to vertebrate placodes.

Insect Tc-six4 marks a unit with similarity to vertebrate placodes.
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昆虫 Tc-64 标记了一个与脊椎动物基板相似的单位

DOI:
10.1016/j.ydbio.2010.10.024
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发表时间:
2010
影响因子:
2.7
通讯作者:
Bucher
Bucher
中科院分区:
生物学3区
文献类型:
--
作者:
Posnien;Koniszewski;Bucher

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颅基板是发育中的脊椎动物头部的特化外胚层区域,其产生神经内分泌系统的神经和非神经细胞类型以及视觉、嗅觉和听觉系统的感觉器官。颅基板从panplacodal区域发展而来,该区域由眼睛缺失/Eya和两个“six homeobox”家族成员(sine oculis/six 1和six 4)的基因特异性标记。以往认为,颅板是脊椎动物进化的新产物。然而,来自非脊椎动物脊索动物的数据表明,在脊索动物祖先中已经进化出了基板状结构。在这里,我们确定了甲虫赤拟谷盗的胚胎头部的形态结构与基板状功能。它由泛基板标记Tc-six 4,Tc-eya和Tc-sine oculis/six 1(Tc-six 1)的直系同源物标记,并表达已知参与脊椎动物腺垂体基板发育的几个基因。此外,它有助于表皮和神经组织。我们确定Tc-six 4作为这种结构的特异性标记,我们称之为昆虫头部基板。最后,我们揭示了泛板基因Tc-six 4,Tc-eya和Tc-six 1的调控基因网络,并确定它们为头部表皮图案化基因。我们在昆虫中发现的基板状结构表明,基板前体已经存在于双侧动物的最后一个共同祖先中。
Cranial placodes are specialized ectodermal regions in the developing vertebrate head that give rise to both neural and non-neural cell types of the neuroendocrine system and the sense organs of the visual, olfactory and acoustic systems. The cranial placodes develop from a panplacodal region which is specifically marked by genes of the eyes absent/eya and two “six homeobox” family members (sine oculis/six1 and six4). It had been believed that cranial placodes are evolutionary novelties of vertebrates. However, data from non-vertebrate chordates suggest that placode-like structures evolved in the chordate ancestor already. Here, we identify a morphological structure in the embryonic head of the beetle Tribolium castaneum with placode-like features. It is marked by the orthologs of the panplacodal markers Tc-six4, Tc-eya and Tc-sine oculis/six1 (Tc-six1) and expresses several genes known to be involved in adenohypophyseal placode development in vertebrates. Moreover, it contributes to both epidermal and neural tissues. We identify Tc-six4 as a specific marker for this structure that we term the insect head placode. Finally, we reveal the regulatory gene network of the panplacodal genes Tc-six4, Tc-eya and Tc-six1 and identify them as head epidermis patterning genes. Our finding of a placode-like structure in an insect suggests that a placode precursor was already present in the last common ancestor of bilaterian animals.
与脊椎动物中脑/后脑边界区相比,果蝇中的近头领地表现出相似性和差异。
DOI: 10.1186/1749-8104-2-23
发表时间: 2007-11-05
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影响因子: 3.6
作者:
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文昌鱼和斑马鱼中 BF-1 表达的保守性表明,有助于脊椎动物端脑的前部细胞类型的进化祖先
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发表时间: 1998
影响因子: 2.4
作者:
H. Toresson;J. Martínez;Anne Bardsley;X. Caubit;S. Krauss
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DOI: --
发表时间: 2001
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影响因子: --
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发表时间: 2007-08
影响因子: 7.3
作者:
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DOI: 10.1046/j.1525-142x.2002.02021.x
发表时间: 2002-09-01
影响因子: 2.9
作者:
Boorman, CJ;Shimeld, SM
通讯作者: Shimeld, SM