Effect of neuromuscular taping on musculoskeletal disorders secondary to the use of aromatase inhibitors in breast cancer survivors: a pragmatic randomised clinical trial.
Effect of neuromuscular taping on musculoskeletal disorders secondary to the use of aromatase inhibitors in breast cancer survivors: a pragmatic randomised clinical trial.
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DOI：
10.1186/s12906-018-2236-3
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发表时间：
2018-06-11
影响因子：
--
通讯作者：
Cuesta-Vargas AI
中科院分区：
文献类型：
--
作者：
Conejo I;Pajares B;Alba E;Cuesta-Vargas AI
与他莫昔芬相比，芳香酶抑制剂可降低绝经后女性乳腺癌复发率约30%，但治疗方法不同。不幸的是，近一半服用人工智能的女性报告了人工智能相关关节痛(AIA)，导致三分之一的患者放弃治疗，这可能导致癌症复发。本研究的目的是评估神经肌肉贴敷术(NMT)在接受BC治疗的妇女AIA中的疗效。这项研究包括40名从维多利亚医院(西班牙马拉加)接受内分泌治疗(AIS或TMX)的BC幸存者患有AIA。患者被随机分到两组中的一组，进行这项先导研究：A.安慰剂干预B.Real NMT。临床资料包括病史、握力、痛觉测量、问卷调查和VAS评分。在研究完成之前，也就是5周后，已经进行了三次干预。这项初步研究的主要目标是通过减少20%的VAS来改善疼痛。两组干预后VAS(p = 0.009)、全球健康状况/生活质量(p = 0.005)、疲劳(p = 0.0 1)和疼痛(p = 0.0 4)等指标有显著差异。AIS治疗下NMT对MSCM的干预改善了他们的主观痛感。此外，这段录音还对与生活质量相关的变量产生了影响。这项先导性研究可能是其他人支持使用NMT治疗AIAS的基础，从而改善他们的幸福感，降低辍学率。ClinicalTrials.gov标识：NCT02406794。于2015年4月2日注册，追溯注册。
Aromatase inhibitors reduce breast cancer recurrence rates in postmenopausal women by about 30% compared with tamoxifen while treatments differ. Unfortunately, nearly half of women taking AIs report AI-associated arthralgia (AIA), leading to therapy abandon in on third of patients, which could lead to cancer recurrence. The purpose of the current study was to evaluate the effectiveness of Neuromuscular Taping (NMT) in the treatment of AIA in women who have been treated of BC. This study included 40 BC survivors receiving endocrine therapy (either AIs or TMX) from Hospital Universitario Virgen de la Victoria (Málaga, Spain) suffered from AIA. Patients were randomized to one of the two groups that made this pilot study: A. Placebo intervention B. Real NMT. Clinical data were collected from medical history, grip strength, algometry measured, questionnaires and VAS scale. There have been three interventions prior to the completion of the study, 5 weeks later. The primary objective of this pilot study was to achieve an improvement of pain by 20% decrease of VAS. Significant differences in measures of VAS (p = 0.009), global health status/QoL (p = 0.005), fatigue (p = 0.01) and pain (p = 0.04) were observed post intervention with NMT. An intervention by NMT to MSCM under treatment with AIs improves their subjective sensation of pain. In addition, this taping had an impact on variables related to the quality of life. This pilot study may be the basis for others to support the use of NMT for the treatment of AIAs, thereby improving their well-being and reducing the dropout rate. ClinicalTrials.gov Identifier: NCT02406794. Registered on 2 April 2015 Retrospectively registered.
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影响因子：
4
作者：
Henry, N. Lynn;Conlon, Anna;Harte, Steven E.
通讯作者：
Harte, Steven E.
影响因子：
3.8
作者：
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Ramírez-Vélez R
影响因子：
45.3
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通讯作者：
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影响因子：
3.8
作者：
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通讯作者：
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影响因子：
3.7
作者：
Bower JE;Greendale G;Crosswell AD;Garet D;Sternlieb B;Ganz PA;Irwin MR;Olmstead R;Arevalo J;Cole SW
通讯作者：
Cole SW