Consensus proposals for classification of the family Hepeviridae.
Consensus proposals for classification of the family Hepeviridae.
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共识提案，分类赫普维里德科。
DOI：
10.1099/vir.0.068429-0
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发表时间：
2014-10
期刊：
影响因子：
--
通讯作者：
Purdy MA
中科院分区：
文献类型：
--
作者：
Smith DB;Simmonds P;Members Of The International Committee On The Taxonomy Of Viruses Study Group;Jameel S;Emerson SU;Harrison TJ;Meng XJ;Okamoto H;Van der Poel WHM;Purdy MA
肝炎病毒科由正链RNA病毒组成，可感染多种哺乳动物物种，包括鸡和鳟鱼。这些病毒的一个子集感染人类并可引起自限性急性肝炎，在免疫抑制的个体中可能变成慢性肝炎。目前发表的关于肝炎病毒科分类学划分的描述在物种和基因型分配方面是矛盾的。通过对现有序列信息的分析，我们提出了一种分类方案，将该科分为正戊型肝炎病毒属（所有哺乳动物和禽类戊型肝炎病毒（HEV）分离株）和鱼肝病毒属（切喉鳟鱼病毒）。正疱疹病毒属的物种被指定为正疱疹病毒A（从人、猪、野猪、鹿、猫鼬、兔子和骆驼中分离）、正疱疹病毒B（从鸡中分离）、正疱疹病毒C（从大鼠、大鼬、亚洲麝香鼩、雪貂和水貂中分离）和正疱疹病毒D（从蝙蝠中分离）。还提出了在人类和大鼠hev中指定基因型的建议。该分级系统与肝炎病毒的系统发育一致，属、种和基因型的三个分类水平与氨基酸序列之间的成对距离范围一致，并反映出不连续性。采用这一系统将避免在分类标识符中使用主机名，并为新变体的分配提供一个逻辑框架。
The family Hepeviridae consists of positive-stranded RNA viruses that infect a wide range of mammalian species, as well as chickens and trout. A subset of these viruses infects humans and can cause a self-limiting acute hepatitis that may become chronic in immunosuppressed individuals. Current published descriptions of the taxonomical divisions within the family Hepeviridae are contradictory in relation to the assignment of species and genotypes. Through analysis of existing sequence information, we propose a taxonomic scheme in which the family is divided into the genera Orthohepevirus (all mammalian and avian hepatitis E virus (HEV) isolates) and Piscihepevirus (cutthroat trout virus). Species within the genus Orthohepevirus are designated Orthohepevirus A (isolates from human, pig, wild boar, deer, mongoose, rabbit and camel), Orthohepevirus B (isolates from chicken), Orthohepevirus C (isolates from rat, greater bandicoot, Asian musk shrew, ferret and mink) and Orthohepevirus D (isolates from bat). Proposals are also made for the designation of genotypes within the human and rat HEVs. This hierarchical system is congruent with hepevirus phylogeny, and the three classification levels (genus, species and genotype) are consistent with, and reflect discontinuities in the ranges of pairwise distances between amino acid sequences. Adoption of this system would include the avoidance of host names in taxonomic identifiers and provide a logical framework for the assignment of novel variants.
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影响因子：
13.5
作者：
Smith, Donald B.;Bukh, Jens;Kuiken, Carla;Muerhoff, A. Scott;Rice, Charles M.;Stapleton, Jack T.;Simmonds, Peter
通讯作者：
Simmonds, Peter
影响因子：
13.5
作者：
Kuiken, Carla;Combet, Christophe;Simmonds, Peter
通讯作者：
Simmonds, Peter
德国挪威大鼠中的新型戊型肝炎病毒基因型
影响因子：
11.8
作者：
Johne R;Heckel G;Plenge-Bönig A;Kindler E;Maresch C;Reetz J;Schielke A;Ulrich RG
通讯作者：
Ulrich RG
影响因子：
11.8
作者：
Lack JB;Volk K;Van Den Bussche RA
通讯作者：
Van Den Bussche RA
影响因子：
3.8
作者：
Bilic, Lvana;Jaskulska, Barbara;Hess, Michael
通讯作者：
Hess, Michael