A perspective on the mobilization, localization and delivery of molecules in the crowded bacterial cytoplasm.
A perspective on the mobilization, localization and delivery of molecules in the crowded bacterial cytoplasm.
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拥挤的细菌细胞质中分子的动员、定位和传递的视角。
DOI：
10.21775/cimb.014.039
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发表时间：
2012
影响因子：
3.1
通讯作者：
J. Trevors
中科院分区：
文献类型：
--
作者：
J. Trevors
已经假设分子在细菌细胞质中的扩散是在没有细胞质流动的情况下移动分子的机制。然而，是否存在一种未被发现的机制，可以调动细胞质及其分子内容物，并将tRNA递送到特定细菌细胞质位置的特定核糖体？将特定的tRNA（以及mRNA转录物和核糖体）和细胞分裂蛋白动员到特定的细胞内位置可能表明需要指令和/或机制。另一种选择是，细胞质中的分子拥挤足以使mRNA、核糖体和tRNA之间温和接触。或者，细菌细胞质（及其内容物）被动员，其结果是分子之间的碰撞比扩散机制更温和，这是否合理？一种假设是，细胞质和分子动员和空间组织可能是由热红外（IR）辐射中的光子和细胞质中禁区（EZ）水的产生驱动的。
It has been assumed that diffusion of molecules in the bacterial cytoplasm is the mechanism that moves molecules in the absence of cytoplasmic streaming. However, is there an undiscovered mechanism present that mobilizes cytoplasm and its molecular contents, and delivers tRNAs to specific ribosomes at specific bacterial cytoplasmic locations? Mobilization of specific tRNA (and also mRNA transcripts and ribosomes) and cell division proteins to specific intracellular locations may suggest that instructions and/or mechanism(s) are needed. The alternative is that molecular crowding in the cytoplasm is sufficient for gentle contact between mRNA, ribosomes and tRNA. Or is it plausible that the bacterial cytoplasm (and its contents) are mobilized with the outcome being more gentle collisions between molecules than by a diffusion only mechanism? One hypothesis is that cytoplasmic and molecule mobilization and spatial organization are possibly driven by the photons in thermal infrared (IR) radiation and generation of exclusion zone (EZ) water in the cytoplasm.
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DOI：
10.1021/jp908163w
发表时间：
2009-10-22
期刊：
The journal of physical chemistry. B
影响因子：
--
作者：
Chai B;Yoo H;Pollack GH
通讯作者：
Pollack GH
细菌核糖体组装的生物物理学研究。
影响因子：
6.8
作者：
Williamson,JamesR
通讯作者：
Williamson,JamesR
假设：水凝胶环境中的生命起源。
DOI：
10.1016/j.pbiomolbio.2004.07.003
发表时间：
2005
期刊：
Progress in biophysics and molecular biology.
影响因子：
--
作者：
Trevors,JackT;Pollack,GeraldH
通讯作者：
Pollack,GeraldH
影响因子：
8.6
作者：
Golding, I;Cox, EC
通讯作者：
Cox, EC