Diacylglycerol kinases as sources of phosphatidic acid.

Diacylglycerol kinases as sources of phosphatidic acid.
复制标题

DOI:
10.1016/j.bbalip.2009.02.010
复制
发表时间:
2009-09
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
Topham MK
Topham MK
中科院分区:
其他
文献类型:
--
作者:
Cai J;Abramovici H;Gee SH;Topham MK

文献摘要

参考文献

被引文献

相似文献

有十种哺乳动物二酰基甘油激酶(DGK),其主要作用是终止二酰基甘油(DAG)信号传导。然而,越来越明显的是,DGK也通过其产物磷脂酸(PA)影响信号传导事件。在某些情况下,它们通过与蛋白质结合,然后通过产生PA来改变其活性。在其他情况下,DGK凭借其提供PA用于合成磷脂酰肌醇(PtdIn)的能力广泛地调节信号传导事件。
There are ten mammalian diacylglycerol kinases (DGKs) whose primary role is to terminate diacylglycerol (DAG) signaling. However, it is becoming increasingly apparent that DGKs also influence signaling events through their product, phosphatidic acid (PA). They do so in some cases by associating with proteins and then modifying their activity by generating PA. In other cases, DGKs broadly regulate signaling events by virtue of their ability to provide PA for the synthesis of phosphatidylinositols (PtdIns).
一种产生溶血磷脂酸的新型酰基甘油激酶可调节前列腺癌细胞中与 EGFR 的串扰。
DOI: 10.1083/jcb.200407123
发表时间: 2005-06-06
期刊: The Journal of cell biology
影响因子: --
作者:
Bektas M;Payne SG;Liu H;Goparaju S;Milstien S;Spiegel S
通讯作者: Spiegel S
DOI: 10.1073/pnas.90.16.7598
发表时间: 1993-08-15
影响因子: 11.1
作者:
GOTO, K;KONDO, H
通讯作者: KONDO, H
DOI: 10.1074/jbc.m802866200
发表时间: 2008-07-18
影响因子: 4.8
作者:
Han, Gil-Soo;O'Hara, Laura;Carman, George M.
通讯作者: Carman, George M.
DOI: 10.1016/s0968-0004(98)01200-6
发表时间: 1998-06-01
影响因子: 13.8
作者:
Hodgkin, MN;Pettitt, TR;Wakelam, MJO
通讯作者: Wakelam, MJO