Socioeconomic Status and Interest in Genetic Testing in a US-Based Sample.
Socioeconomic Status and Interest in Genetic Testing in a US-Based Sample.
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DOI：
10.3390/healthcare10050880
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发表时间：
2022-05-10
期刊：
影响因子：
--
通讯作者：
Wang C
中科院分区：
文献类型：
--
作者：
Dusic EJ;Bowen DJ;Bennett R;Cain KC;Theoryn T;Velasquez M;Swisher E;Brant JM;Shirts B;Wang C
癌症是一个重大的负担，特别是对社会经济地位低的个体。基因检测可以提供有关个人患癌症风险的信息，并指导未来的筛查和预防服务。然而，有显著的经济障碍，特别是对低社会经济地位的个人。本研究采用遗传风险早期检测（EDGE）研究的患者基线调查（n = 2329）来评估社会经济地位与追求遗传性癌症基因检测的兴趣之间的关系。对两种兴趣结果进行了分析，即对基因检测的总体兴趣和对免费或低成本基因检测的兴趣。许多人口统计学和社会经济地位变量是基因检测兴趣的预测因子，包括教育、收入和麦克阿瑟主观社会量表（SSS）。在控制了医疗保健系统、年龄和性别之后，拥有较高的教育水平和较高的家庭收入与更大的普遍兴趣相关。如果基因检测是免费或低成本的，SSS越低，人们对基因检测的兴趣就越大。如果基因检测是预防医学的未来，则需要开展更多的工作，使低社会经济地位群体能够获得这一选择，并确保这些服务被最得不到服务的人群使用。
Cancer is a significant burden, particularly to individuals of low socioeconomic status (SES). Genetic testing can provide information about an individual’s risk of developing cancer and guide future screening and preventative services. However, there are significant financial barriers, particularly for individuals of low SES. This study used the Early Detection of Genetic Risk (EDGE) Study’s patient baseline survey (n = 2329) to evaluate the relationship between socioeconomic status and interest in pursuing hereditary cancer genetic testing. Analysis was completed for two interest outcomes—overall interest in genetic testing and interest in genetic testing if the test were free or low cost. Many demographic and SES variables were predictors for interest in genetic testing, including education, income, and MacArthur Subjective Social Scale (SSS). After controlling for the healthcare system, age, and gender, having a higher education level and a higher household income were associated with greater general interest. Lower SSS was associated with greater interest in genetic testing if the test was free or low cost. If genetic testing is the future of preventative medicine, more work needs to be performed to make this option accessible to low-SES groups and to ensure that those services are used by the most underserved populations.
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影响因子：
6.2
作者：
Doubeni CA;Laiyemo AO;Major JM;Schootman M;Lian M;Park Y;Graubard BI;Hollenbeck AR;Sinha R
通讯作者：
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影响因子：
5
作者：
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影响因子：
3.5
作者：
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通讯作者：
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影响因子：
254.7
作者：
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通讯作者：
Brawley, Otis W.
影响因子：
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作者：
Singh GK;Jemal A
通讯作者：
Jemal A