A scoping review for building a criticality-based conceptual framework of altered states of consciousness.
A scoping review for building a criticality-based conceptual framework of altered states of consciousness.
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DOI：
10.3389/fnsys.2023.1085902
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发表时间：
2023
影响因子：
3
通讯作者：
Duclos, Catherine
中科院分区：
文献类型：
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作者：
Gervais, Charles;Boucher, Louis-Philippe;Villar, Guillermo Martinez;Lee, UnCheol;Duclos, Catherine
关键词：
健康的意识大脑被认为在临界状态附近运行，反映了最佳的信息处理和对外部刺激的高度敏感性。相反，偏离临界状态被假设为引起意识状态改变（ASC）。因此，临界性的测量可能是建立个人意识状态的有效方法。此外，表征偏离临界状态的方向可能有助于制定病理性ASC的治疗策略。本次范围界定审查的目的是评估支持关键性假设的现有证据，以及使用关键性作为ASC的概念框架。使用PRISMA指南，对Web of Science和PubMed从成立到2022年2月7日进行了搜索，以查找与ASC关键性测量相关的文章。N = 427独立论文最初发现的主题。N = 378例被排除，因为它们：与危急程度无关;与意识无关;未提供主要研究的结果;提供模型数据。本研究纳入了N = 49篇独立论文，分为ASC的7个子类别：意识障碍（DOC）（n = 5）;睡眠（n = 13）;麻醉（n = 18）;癫痫（n = 12）;迷幻药和萨满意识状态（n = 4）;谵妄（n = 1）;冥想状态（n = 2）。每个类别包括提示临界状态偏离的文章。虽然大多数研究只能确定临界状态的偏离，但无法确定其方向，但文献中的初步共识是，非快速眼动（NREM）睡眠反映了亚临界状态，癫痫发作反映了超临界状态，迷幻药比正常意识更接近临界状态。这一范围审查表明，虽然文献有限，方法不均匀，ASC的特点是偏离关键性，但其方向在大多数研究中没有明确报告。通过更广泛的研究，临界性可能成为表征ASC的有效和客观的方法，并有助于确定改善病理性大脑状态临界性的治疗途径。此外，我们建议如何麻醉和致幻剂可能被用作神经调节技术，以恢复临界DOC。
The healthy conscious brain is thought to operate near a critical state, reflecting optimal information processing and high susceptibility to external stimuli. Conversely, deviations from the critical state are hypothesized to give rise to altered states of consciousness (ASC). Measures of criticality could therefore be an effective way of establishing the conscious state of an individual. Furthermore, characterizing the direction of a deviation from criticality may enable the development of treatment strategies for pathological ASC. The aim of this scoping review is to assess the current evidence supporting the criticality hypothesis, and the use of criticality as a conceptual framework for ASC. Using the PRISMA guidelines, Web of Science and PubMed were searched from inception to February 7th 2022 to find articles relating to measures of criticality across ASC. N = 427 independent papers were initially found on the subject. N = 378 were excluded because they were either: not related to criticality; not related to consciousness; not presenting results from a primary study; presenting model data. N = 49 independent papers were included in the present research, separated in 7 sub-categories of ASC: disorders of consciousness (DOC) (n = 5); sleep (n = 13); anesthesia (n = 18); epilepsy (n = 12); psychedelics and shamanic state of consciousness (n = 4); delirium (n = 1); meditative state (n = 2). Each category included articles suggesting a deviation of the critical state. While most studies were only able to identify a deviation from criticality without being certain of its direction, the preliminary consensus arising from the literature is that non-rapid eye movement (NREM) sleep reflects a subcritical state, epileptic seizures reflect a supercritical state, and psychedelics are closer to the critical state than normal consciousness. This scoping review suggests that, though the literature is limited and methodologically inhomogeneous, ASC are characterized by a deviation from criticality, though its direction is not clearly reported in a majority of studies. Criticality could become, with more extensive research, an effective and objective way to characterize ASC, and help identify therapeutic avenues to improve criticality in pathological brain states. Furthermore, we suggest how anesthesia and psychedelics could potentially be used as neuromodulation techniques to restore criticality in DOC.
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影响因子：
5.3
作者：
Beliveau, Vincent;Ganz, Melanie;Knudsen, Gitte M.
通讯作者：
Knudsen, Gitte M.
影响因子：
7.8
作者：
Allegrini, Paolo;Paradisi, Paolo;Gemignani, Angelo
通讯作者：
Gemignani, Angelo
影响因子：
11.5
作者：
Ciurleo, Rosella;Bramanti, Placido;Calabro, Rocco Salvatore
通讯作者：
Calabro, Rocco Salvatore
影响因子：
2.9
作者：
Blume C;Del Giudice R;Wislowska M;Lechinger J;Schabus M
通讯作者：
Schabus M
影响因子：
3.2
作者：
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