Body mass index and breast cancer treatment-related lymphedema.
Body mass index and breast cancer treatment-related lymphedema.
复制标题
体重指数和与乳腺癌治疗相关的淋巴水肿。
DOI：
10.1007/s00520-011-1089-9
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发表时间：
2011-06
影响因子：
3.1
通讯作者：
Armer, Jane M.
中科院分区：
文献类型：
--
作者：
Ridner, Sheila H.;Dietrich, Mary S.;Stewart, Bob R.;Armer, Jane M.
主要目的是纵向研究体重指数（BMI）和肥胖对乳腺癌治疗相关性水肿发展的影响。我们问，BMI升高是否会增加水肿风险？在一项前瞻性纵向母研究中，对从138名新诊断的乳腺癌幸存者中收集的去识别数据进行了二次分析，这些幸存者在治疗前基线和术后30个月内进行了手臂体积测量和症状评估。检查了手臂体积和体重数据，这是每次参与者访视期间收集的信息的一部分。在乳腺癌治疗时BMI ≥30的乳腺癌幸存者在诊断后6个月或更长时间发生水肿的可能性是癌症治疗时BMI <30的乳腺癌幸存者的约3.6倍（95%置信区间，C.I.，优势比手术室1.42-9.04，p=0.007）。在存活的前30个月内，BMI普遍增加或BMI升高至30或更高的患者发生迟发性水肿的可能性并不比BMI没有类似变化的患者高。治疗前BMI可能是水肿的风险因素。治疗后体重增加可能不会。需要进一步研究。
The main purpose was to examine longitudinally the influence of body mass index (BMI) and obesity on the development of breast cancer treatment-related lymphedema. We asked, does elevated BMI increase lymphedema risk? A secondary analysis was conducted on de-identified data collected from 138 newly diagnosed breast cancer survivors who had arm volume measurements and symptom assessment at pre-treatment baseline and measurements up to 30 months post-surgery in a prospective longitudinal parent study. Arm volume and weight data, part of the information collected during each participant visit, were examined. Breast cancer survivors whose BMI was ≥30 at the time of breast cancer treatment were approximately 3.6 times more likely to develop lymphedema at 6 months or greater after diagnosis than those with a BMI <30 at the time of cancer treatment (95% confidence interval, C.I., for odds ratio, O.R., 1.42–9.04, p=0.007). Those with a general BMI increase or a BMI rise to 30 or greater during their first 30 months of survivorship were not more likely to develop late-onset lymphedema than those who did not have similar changes in BMI. Pre-treatment BMI may be a risk factor for lymphedema. Weight gain post-treatment may not be. Further research is warranted.
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影响因子：
2.5
作者：
Mak, So Shan;Yeo, Winnie;Kwan, Wing Hong
通讯作者：
Kwan, Wing Hong
影响因子：
2.9
作者：
Kopanski, Z;Wojewoda, T;Kosciuk, T
通讯作者：
Kosciuk, T
影响因子：
13.3
作者：
Clark, B;Sitzia, J;Harlow, W
通讯作者：
Harlow, W
影响因子：
3.1
作者：
Ridner, SH
通讯作者：
Ridner, SH
DOI：
10.1016/s0889-8529(03)00067-7
发表时间：
2003-12-01
影响因子：
4.5
作者：
Bray, GA
通讯作者：
Bray, GA