Astrocytes in Migration
Astrocytes in Migration
复制标题
迁移中的星形胶质细胞
DOI：
10.1007/s11064-016-2089-4
复制
发表时间：
2016
影响因子：
4.4
通讯作者：
Albert Cheung Hoi Yu
中科院分区：
文献类型：
--
作者：
JiangShanZhan;Kai Gao;Rui Chao Chai;Xi Hua Jia;Dao Peng Luo;Guo Ge;Yu Wu Jiang;Yin-wan Wendy Fung;Lina Li;Albert Cheung Hoi Yu
Cell migration is a fundamental phenomenon that underlies tissue morphogenesis, wound healing, immune response, and cancer metastasis. Great progresses have been made in research methodologies, with cell migration identified as a highly orchestrated process. Brain is considered the most complex organ in the human body, containing many types of neural cells with astrocytes playing crucial roles in monitoring normal functions of the central nervous system. Astrocytes are mostly quiescent under normal physiological conditions in the adult brain but become migratory after injury. Under most known pathological conditions in the brain, spinal cord and retina, astrocytes are activated and become hypertrophic, hyperplastic, and up-regulating GFAP based on the grades of severity. These three observations are the hallmark in glia scar formation—astrogliosis. The reactivation process is initiated with structural changes involving cell process migration and ended with cell migration. Detailed mechanisms in astrocyte migration have not been studied extensively and remain largely unknown. Here, we therefore attempt to review the mechanisms in migration of astrocytes.
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影响因子：
--
作者：
Schousboe A;Scafidi S;Bak LK;Waagepetersen HS;McKenna MC
通讯作者：
McKenna MC
DOI：
10.1201/b14602-12
发表时间：
2013
期刊：
--
影响因子：
--
作者：
Masataka Yamao;Honda Naoki;Shin Ishii
通讯作者：
Masataka Yamao;Honda Naoki;Shin Ishii
影响因子：
56.9
作者：
Behrens, J;Jerchow, BA;Birchmeier, W
通讯作者：
Birchmeier, W
DOI：
10.1177/1073858411423441
发表时间：
2012-12
期刊：
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
影响因子：
--
作者：
Sun D;Jakobs TC
通讯作者：
Jakobs TC
影响因子：
6.7
作者：
Cayre M;Canoll P;Goldman JE
通讯作者：
Goldman JE