Stockpiling drugs for an avian influenza outbreak: examining the surge in oseltamivir prescriptions during heightened media coverage of the potential for a worldwide pandemic.
Stockpiling drugs for an avian influenza outbreak: examining the surge in oseltamivir prescriptions during heightened media coverage of the potential for a worldwide pandemic.
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DOI：
10.1086/596609
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发表时间：
2009-04
影响因子：
4.5
通讯作者：
Lautenbach E
中科院分区：
文献类型：
--
作者：
Gasink LB;Linkin DR;Fishman NO;Bilker WB;Weiner MG;Lautenbach E
2005年秋季，广泛报告了个人储存奥司他韦以备H5N1流感病毒感染暴发时使用。本研究旨在确定奥司他韦处方的适应症，以确定非用于季节性流感的奥司他韦是否被不恰当地食用，并比较可能储存了奥司他韦的人和没有储存奥司他韦的人对禽流感的知识、理解、关注和期望。调查以评估奥司他韦的使用模式并评估对禽流感的看法。在2005年9月1日至2005年12月31日期间接受奥司他韦处方的109名门诊患者和825名匹配的对照受试者。109张处方中，有36张（33.0%）是给符合适应证的患者开的。109名患者中有68名（62.4%）接受了奥司他韦治疗，825名患者中有440名（53.3%）未接受奥司他韦治疗。只有2名不打算立即服用奥司他韦的处方接受者报告说他们服用了奥司他韦。可能打算储存奥司他韦的人比那些不可能储存它的人年龄更大，而且往往是白人。他们还报告说，与那些不太可能储备的国家相比，他们更担心禽流感，更经常预计禽流感会传播到美国，但对其他问卷项目的回答没有显著差异。2005年秋天开出的奥司他韦处方中，很大一部分可能是为了个人储备。参与者对问卷项目的回答的相似性表明，教育运动可能不是在感染威胁期间减少抗菌药物储存的有效方法。促进提供者之间适当的处方做法可能是尽量减少个人库存的较好方法。
During fall 2005, personal stockpiling of oseltamivir for use during an outbreak of H5N1 influenza virus infection was widely reported. The present study aimed to identify indications for oseltamivir prescriptions to determine whether oseltamivir that was not intended for seasonal influenza was inappropriately consumed and to compare persons who were likely to have stockpiled oseltamivir and those who did not with respect to their knowledge, understanding, concerns, and expectations regarding avian influenza. Survey to evaluate usage patterns for oseltamivir and assess views about avian influenza. A total of 109 outpatients who received a prescription for oseltamivir between September 1, 2005, and December 31, 2005, and 825 matched control subjects. Of 109 prescriptions, 36 (33.0%) were prescribed for patients with appropriate indications. Sixty-eight (62.4%) of 109 patients identified as having received oseltamivir and 440 (53.3%) of 825 individuals identified as not having received it responded to the questionnaire. Only 2 prescription recipients whose oseltamivir was not intended for immediate consumption reported that they had consumed the oseltamivir. Persons who probably intended to stockpile oseltamivir were older and more often white than those unlikely to stockpile it. They also reported greater worry about avian influenza and more often expected avian influenza to spread to the United States than those unlikely to stockpile, but there were no significant differences in responses to other questionnaire items. A large proportion of the oseltamivir prescriptions written in fall 2005 were probably intended for personal stockpiling. Similarities in participants’ responses to questionnaire items suggest that educational campaigns may not be an effective method to curtail stockpiling of antimicrobial medications during an infectious threat. Promoting appropriate prescribing practices among providers may be a better means by which to minimize personal stockpiling.
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影响因子：
4.5
作者：
M'ikanatha NM;Julian KG;Kunselman AR;Aber RC;Rankin JT;Lautenbach E
通讯作者：
Lautenbach E
DOI：
10.1331/154434503321831085
发表时间：
2003-05-01
期刊：
Journal of the American Pharmacists Association : JAPhA
影响因子：
--
作者：
Brinker, Allen;Pamer, Carol;Beitz, Julie
通讯作者：
Beitz, Julie
影响因子：
3.6
作者：
Richman, PB;Garra, G;Cody, R
通讯作者：
Cody, R
影响因子：
11.8
作者：
Ortiz, Justin R.;Shay, David K.;Strausbaugh, Larry J.
通讯作者：
Strausbaugh, Larry J.
影响因子：
2.6
作者：
Shaffer, D;Armstrong, G;Murphy, D
通讯作者：
Murphy, D