Size-segregated particle number concentrations and respiratory emergency room visits in Beijing, China.
Size-segregated particle number concentrations and respiratory emergency room visits in Beijing, China.
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DOI：
10.1289/ehp.1002203
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发表时间：
2011-04
影响因子：
10.4
通讯作者：
Franck U
中科院分区：
文献类型：
--
作者：
Leitte AM;Schlink U;Herbarth O;Wiedensohler A;Pan XC;Hu M;Richter M;Wehner B;Tuch T;Wu Z;Yang M;Liu L;Breitner S;Cyrys J;Peters A;Wichmann HE;Franck U
许多研究调查了颗粒物（PM）浓度与呼吸道疾病之间的联系。本研究的目的是分析中国北京不同粒径组分对呼吸系统健康的作用。3 nm ~ 1 μm粒径分布数据；PM10 （PM≤10 μm）、二氧化氮（NO2）、二氧化硫浓度；及2004年3月至2006年12月逐日收集的气象变量。同时，获得了北京大学第三医院呼吸系统疾病的每日急诊室就诊次数。我们在控制气象和其他时变协变量的情况下，用单污染物和双污染物广义加性模型估计污染物的影响。使用多项式分布滞后、累积效应和单滞后模型估计时间延迟关联。呼吸ERV与NO2浓度和100-1,000 nm颗粒数或表面积浓度的关联程度相似，即在空气污染浓度增加的四分位数范围内，呼吸ERV增加约5%。一般来说，< 50 nm的颗粒与ERV无正相关，而50 - 100 nm的颗粒与呼吸道ERV负相关，两者都是超细颗粒的一部分。双污染物模型对二氧化氮的影响估计最为一致。北京目前的空气污染水平与呼吸道ERV呈负相关。在北京，NO2浓度似乎是评估环境空气污染对呼吸系统健康总体影响的更好替代指标，而不是PM10或颗粒数浓度。
The link between concentrations of particulate matter (PM) and respiratory morbidity has been investigated in numerous studies. The aim of this study was to analyze the role of different particle size fractions with respect to respiratory health in Beijing, China. Data on particle size distributions from 3 nm to 1 μm; PM10 (PM ≤ 10 μm), nitrogen dioxide (NO2), and sulfur dioxide concentrations; and meteorologic variables were collected daily from March 2004 to December 2006. Concurrently, daily counts of emergency room visits (ERV) for respiratory diseases were obtained from the Peking University Third Hospital. We estimated pollutant effects in single- and two-pollutant generalized additive models, controlling for meteorologic and other time-varying covariates. Time-delayed associations were estimated using polynomial distributed lag, cumulative effects, and single lag models. Associations of respiratory ERV with NO2 concentrations and 100–1,000 nm particle number or surface area concentrations were of similar magnitude—that is, approximately 5% increase in respiratory ERV with an interquartile range increase in air pollution concentration. In general, particles < 50 nm were not positively associated with ERV, whereas particles 50–100 nm were adversely associated with respiratory ERV, both being fractions of ultrafine particles. Effect estimates from two-pollutant models were most consistent for NO2. Present levels of air pollution in Beijing were adversely associated with respiratory ERV. NO2 concentrations seemed to be a better surrogate for evaluating overall respiratory health effects of ambient air pollution than PM10 or particle number concentrations in Beijing.
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影响因子：
10
作者：
Knol AB;de Hartog JJ;Boogaard H;Slottje P;van der Sluijs JP;Lebret E;Cassee FR;Wardekker JA;Ayres JG;Borm PJ;Brunekreef B;Donaldson K;Forastiere F;Holgate ST;Kreyling WG;Nemery B;Pekkanen J;Stone V;Wichmann HE;Hoek G
通讯作者：
Hoek G
超铁颗粒在空气颗粒质量与心血管健康之间关联中的潜在作用。
影响因子：
10.4
作者：
Delfino RJ;Sioutas C;Malik S
通讯作者：
Malik S
影响因子：
6.3
作者：
Krudysz, M.;Moore, K.;Froines, J.
通讯作者：
Froines, J.
影响因子：
11.8
作者：
Kan, Haidong;London, Stephanie J.;Chen, Bingheng
通讯作者：
Chen, Bingheng
影响因子：
6.8
作者：
AKAIKE, H
通讯作者：
AKAIKE, H