Prevalence and risk factors for heterotopic gastric mucosa of the upper esophagus among men undergoing routine screening colonoscopy.
Prevalence and risk factors for heterotopic gastric mucosa of the upper esophagus among men undergoing routine screening colonoscopy.
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接受常规结肠镜筛查的男性上食管异位胃粘膜的患病率和危险因素。
DOI：
10.1111/dote.12221
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Rubenstein,JH
中科院分区：
文献类型：
--
作者：
Govani,SM;Metko,V;Rubenstein,JH
食管上段胃粘膜异位（入口斑）的患病率范围很广，这取决于检查的方法和细节。入口补丁被认为是一种先天性畸形，很少导致症状。我们的目的是量化非转诊人群中入口斑的患病率，并确定是否存在任何风险因素或相关症状。在两个临床站点进行常规结肠镜检查的年龄在50至79岁之间的男性被招募进行上消化道内窥镜检查。提示内镜医师检查入口贴片的存在。在入组的822例患者中，795例有关于入口贴片存在的数据。其中，55例（6.9%）有入口斑块。受教育程度呈负相关（优势比[OR]高等学历与高中或以下学历= 0.310; 95%置信区间[CI] = 0.111，0.869），烟草使用与入口斑块的存在呈正相关（当前与从不吸烟者OR = 2.87; 95%CI = 1.23，6.69;以前与从不吸烟者OR = 1.93; 95%CI = 0.922，4.02）。在结肠癌筛查的横断面研究中，入口斑片很常见，与症状无关。烟草的使用似乎与入口斑块的存在有关。
The prevalence of heterotopic gastric mucosa of the upper esophagus (inlet patch) has a wide range depending on the method and detail of examination. The inlet patch is believed to be a congenital malformation that rarely leads to symptoms. We aimed to quantify the prevalence of the inlet patch in a non-referred population and determine if there are any risk factors or associated symptoms. Men between ages 50 and 79 presenting for routine colonoscopy at two clinical sites were recruited to undergo an upper endoscopy. Endoscopists were prompted to examine for the presence of the inlet patch. Of the 822 enrolled patients, 795 had data regarding the presence of an inlet patch. Of these, 55 (6.9%) had an inlet patch identified. Education was inversely associated (odds ratio [OR] advanced degree vs. high school or less = 0.310; 95% confidence interval [CI] = 0.111, 0.869), and tobacco use was positively associated with the presence of an inlet patch (current vs. never smokers OR = 2.87; 95% CI = 1.23, 6.69; former vs. never smokers OR = 1.93; 95% CI = 0.922, 4.02). No association between the inlet patch and symptoms of heartburn, globus, or dysphagia was found. In a cross-sectional study of colon cancer screenees, inlet patches were common and were not associated with symptoms. Tobacco use appears to be associated with the presence of an inlet patch.
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DOI：
--
发表时间：
1972
期刊：
影响因子：
--
作者：
G. Nelson
通讯作者：
G. Nelson
影响因子：
15.9
作者：
GRUNDY, SM;MOK, HYI;BERMAN, M
通讯作者：
BERMAN, M
同时测量家族性高胆固醇血症中极低和低密度脂蛋白的载脂蛋白 B 周转率。
影响因子：
5.3
作者：
A. Soutar;N. B. Myant;G. Thompson
通讯作者：
G. Thompson
食蟹猴中脱辅基蛋白 B 的代谢：低密度脂蛋白脱辅基蛋白 B 独立产生的证据。
DOI：
10.1152/ajpendo.1983.244.2.e196
发表时间：
1983
期刊：
The American journal of physiology
影响因子：
--
作者：
Goldberg,IJ;Le,NA;Ginsberg,HN;PaternitiJr,JR;Brown,WV
通讯作者：
Brown,WV
第211章-鞘磷脂脂质沉积症（尼曼匹克病）
DOI：
--
发表时间：
1979
期刊：
影响因子：
--
作者：
D. Percy
通讯作者：
D. Percy