Cortical development and asymmetric cell divisions

Cortical development and asymmetric cell divisions
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皮质发育和不对称细胞分裂

DOI:
10.1007/s11515-012-1235-x
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发表时间:
2012-06
期刊:
Frontiers in Biology
影响因子:
--
通讯作者:
Yan Zhou
Yan Zhou
中科院分区:
其他
文献类型:
--
作者:
Yan Zhou

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The development of the mammalian neocortex involves rounds of symmetric and asymmetric cell division of neural progenitors to fulfill needs of both self-renewal of progenitors and production of differentiated progenies such as neurons and glia. The machinery for asymmetric cell division is evolutionarily conserved and extensively used in organogenesis and homeostasis of adult tissues. Here we summarize recent progress regarding cellular characteristics of different types of neural progenitors in mammals, highlighting how asymmetric cell division is utilized during cortical development.
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