Isolation of point mutations in bacteriophage Mu attachment regions cloned in a lambda::mini-Mu phage.
Isolation of point mutations in bacteriophage Mu attachment regions cloned in a lambda::mini-Mu phage.
复制标题
分离 lambda::mini-Mu 噬菌体中克隆的噬菌体 Mu 附着区的点突变。
DOI:
10.1073/pnas.83.16.6012
复制
发表时间:
1986
影响因子:
11.1
通讯作者:
Howe,MM
中科院分区:
文献类型:
--
作者:
Burlingame,RP;Obukowicz,MG;Lynn,DL;Howe,MM
Twenty-one derivatives of a lambda::mini-Mu phage containing point mutations in the Mu attachment regions were isolated after mutD mutagenesis and selection for relief from Mu-specific replicative interference of lambda growth. DNA sequence analysis revealed that the single left-end mutant had suffered a T----C transition at position 1 of the Mu sequence, while the remaining 20 right-end mutants contained single base-pair insertions or deletions within the terminal 19 base pairs. A genetic assay showed that the right-end mutations revealed by sequencing were necessary for relief of the replicative inhibition of lambda growth. The properties of these mutants suggest that the terminal 2-base-pair and subterminal 8-base-pair inverted repeats are important for Mu-specific replicative transposition.
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DOI:
10.1016/0005-2736(81)90243-1
发表时间:
1981-01-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子:
--
作者:
BIBER, J;STIEGER, B;MURER, H
通讯作者:
MURER, H
DOI:
--
发表时间:
1983
期刊:
Membrane Biochemistry
影响因子:
--
作者:
T. Jean;P. Ripoche;P. Poujeol
通讯作者:
P. Poujeol
DOI:
10.1016/s0021-9258(19)44440-2
发表时间:
1973-01
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
U. Hopfer;K. Nelson;J. Perrotto;K. Isselbacher
通讯作者:
U. Hopfer;K. Nelson;J. Perrotto;K. Isselbacher
影响因子:
3.9
作者:
B. States;J. Lee;S. Segal
通讯作者:
S. Segal
DOI:
10.1016/0005-2736(79)90427-9
发表时间:
1979
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
P. McNamara;L. Pepe;S. Segal
通讯作者:
S. Segal